Back Pain

17
Pipeline Programs
9
Companies
10
Clinical Trials
13
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
1
1
15
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 12 programs with unclassified modality

On Market (13)

Approved therapies currently available

U
CHILDREN'S MOTRINApproved
ibuprofen
Unknown Company
Nonsteroidal Anti-inflammatory Drug [EPC]oral1996
U
IBUApproved
ibuprofen
Unknown Company
oral1986
U
IBU-TABApproved
ibuprofen
Unknown Company
oral1988
U
IBU-TAB 200Approved
ibuprofen
Unknown Company
oral1988
U
IBUPRINApproved
ibuprofen
Unknown Company
oral1987
U
IBUPROFENApproved
ibuprofen
Unknown Company
oral1987
U
IBUPROHMApproved
ibuprofen
Unknown Company
oral1985
U
JUNIOR STRENGTH IBUPROFENApproved
ibuprofen
Unknown Company
oral1999
U
JUNIOR STRENGTH MOTRINApproved
ibuprofen
Unknown Company
oral1996
U
MIDOL LIQUID GELSApproved
ibuprofen
Unknown Company
oral2002
U
MOTRIN IBApproved
ibuprofen
Unknown Company
oral1984
U
MOTRIN MIGRAINE PAINApproved
ibuprofen
Unknown Company
oral1984
U
RUFENApproved
ibuprofen
Unknown Company
oral1981

Competitive Landscape

9 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
4 programs
1
Tramadol Hydrochloride 50mgPhase 41 trial
Group 2N/A1 trial
painPREMIER cohortN/A1 trial
thermal therapyN/A1 trial
Active Trials
NCT02484937Terminated9Est. Jun 2022
NCT01787565Terminated86Est. Jan 2014
NCT01355653Completed45Est. Jul 2011
+1 more trials
OD
1 program
1
tramadol hydrochloride , acetaminophenPhase 4
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
1
ibuprofenPhase 3Small Molecule1 trial
Active Trials
NCT03003000Completed635Est. Sep 2017
Jerusalem Pharmaceuticals
Jerusalem PharmaceuticalsIsrael - Ramallah
1 program
1
GaAlAs 808nm laserPhase 2/31 trial
Active Trials
NCT02665507Completed42Est. Jul 2024
Aspen Medical products
2 programs
Aspen Horizon 627 LSON/A1 trial
Peak Scoliosis Bracing SystemN/A1 trial
Active Trials
NCT03100097Terminated62Est. Dec 2017
NCT02643290Completed20Est. Jan 2017
Compass Therapeutics
1 program
Freedom SCS SystemN/A
Curonix
CuronixFL - Pompano Beach
1 program
Freedom SCS SystemN/A
Precision BioSciences
1 program
Freedom SCS SystemN/A1 trial
Active Trials
NCT02514590Completed49Est. Jul 2019
Verona Pharma
Verona PharmaUK - London
1 program
The FIT Therapy patchN/A1 trial
Active Trials
NCT04651426Completed54Est. Oct 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerTramadol Hydrochloride 50mg
Boehringer Ingelheimibuprofen
Jerusalem PharmaceuticalsGaAlAs 808nm laser
Verona PharmaThe FIT Therapy patch
Precision BioSciencesFreedom SCS System
Aspen Medical productsPeak Scoliosis Bracing System
PfizerGroup 2
Aspen Medical productsAspen Horizon 627 LSO
PfizerpainPREMIER cohort
Pfizerthermal therapy

Clinical Trials (10)

Total enrollment: 1,756 patients across 10 trials

NCT00290901PfizerTramadol Hydrochloride 50mg

Celebrex vs Tramadol in the Treatment of Chronic Lower Back Pain.

Start: Mar 2006754 patients
Phase 4Completed
NCT03003000Boehringer Ingelheimibuprofen

Ibuprofen/Caffeine Lower Back or Neck Pain Study

Start: Dec 2016Est. completion: Sep 2017635 patients
Phase 3Completed
NCT02665507Jerusalem PharmaceuticalsGaAlAs 808nm laser

Light Therapy for the Treatment of Back Pain in Pilots (LLL&Pilots)

Start: Mar 2018Est. completion: Jul 202442 patients
Phase 2/3Completed
NCT04651426Verona PharmaThe FIT Therapy patch

Use of a Non-medicated Plaster in Chronic Lumbar Back Pain.

Start: Aug 2019Est. completion: Oct 201954 patients
N/ACompleted
NCT02514590Precision BioSciencesFreedom SCS System

Wireless Spinal Cord Stimulation for Chronic Pain

Start: Jul 2016Est. completion: Jul 201949 patients
N/ACompleted
NCT02643290Aspen Medical productsPeak Scoliosis Bracing System

Efficacy of Peak Scoliosis Brace in Pain Management For Adult Scoliosis Patients

Start: Apr 2015Est. completion: Jan 201720 patients
N/ACompleted
NCT02484937PfizerGroup 2

Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts

Start: Jan 2015Est. completion: Jun 20229 patients
N/ATerminated
NCT03100097Aspen Medical productsAspen Horizon 627 LSO

A Prospective, Multicenter, Randomized Control Study To Determine Clinical Effectiveness, Patient Wellness and Cost of Pain Related Care of In-Elastic Lumbar Sacral Orthoses Versus Standard Medical Treatment in Patients Presenting With Acute Low Back Pain In Primary Care Centers (The ARREST Study)

Start: Dec 2013Est. completion: Dec 201762 patients
N/ATerminated
NCT01787565PfizerpainPREMIER cohort

Pilot Evaluation to Assess the Clinical and Economic Impact of Pfizer's Pain Management Program (painPREMIER) in the Treatment of Low Back Pain, in an Occupational Health Care Setting in Finland

Start: Jan 2013Est. completion: Jan 201486 patients
N/ATerminated
NCT01355653Pfizerthermal therapy

Heat Wrap Device Safety With Age and Body Fat

Start: May 2011Est. completion: Jul 201145 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
9 companies competing in this space