Aging

3
Pipeline Programs
13
Companies
11
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
2 programs
1
CP-424,391Phase 21 trial
AD-EasyN/A1 trial
Active Trials
NCT00328055Completed200Est. Jul 2005
NCT00527046Terminated396Est. Oct 2001
Alliance Pharmaceuticals
1 program
1
ClimaraPhase 21 trial
Active Trials
NCT00220454Completed40Est. Mar 2005
Lantheus Medical Imaging
1 program
1
N-acetylcysteinePhase 1/21 trial
Active Trials
NCT01384591CompletedEst. May 2015
City Therapeutics
City TherapeuticsMA - Cambridge
2 programs
InterventionN/A1 trial
None of interventionN/A1 trial
Active Trials
NCT03342729CompletedEst. Mar 2018
NCT05468905RecruitingEst. Dec 2026
Novo Nordisk
Novo NordiskBAGSVAERD DENMARK, Denmark
1 program
D-β-hydroxybutyrate/D 1,3 butanediol monoesterN/A1 trial
Active Trials
NCT05732909Completed25Est. Jan 2024
AB
AP BiosciencesTaiwan - Taipei
1 program
D-β-hydroxybutyrate/D 1,3 butanediol monoesterN/A
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
Long-term Caloric Restriction and Cellular Aging MarkersN/A1 trial
Active Trials
NCT01256840Completed71Est. Aug 2014
Genomics
GenomicsUK - Oxford
1 program
NMNN/A1 trial
Active Trials
NCT06592859Recruiting240Est. Dec 2026
Ambrosia Biosciences
1 program
PlasmaN/A1 trial
Active Trials
NCT02803554CompletedEst. Jan 2018
Soterix Medical
Soterix MedicalNJ - Woodbridge
1 program
tDCSN/A1 trial
Active Trials
NCT05377411CompletedEst. Jun 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Alliance PharmaceuticalsClimara
PfizerCP-424,391
Lantheus Medical ImagingN-acetylcysteine
GenomicsNMN
Soterix MedicaltDCS
Novo NordiskD-β-hydroxybutyrate/D 1,3 butanediol monoester
City TherapeuticsNone of intervention
City TherapeuticsIntervention
Ambrosia BiosciencesPlasma
Johnson & JohnsonLong-term Caloric Restriction and Cellular Aging Markers
PfizerAD-Easy

Clinical Trials (11)

Total enrollment: 972 patients across 11 trials

NCT00220454Alliance PharmaceuticalsClimara

Effect of Estrogen & Stress for Postmenopausal Women

Start: Dec 2002Est. completion: Mar 200540 patients
Phase 2Completed
NCT00527046PfizerCP-424,391

Effects Of An Oral Growth Hormone Secretagogue In Older Functionally Limited Adults

Start: Dec 1999Est. completion: Oct 2001396 patients
Phase 2Terminated
NCT01384591Lantheus Medical ImagingN-acetylcysteine

Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly

Start: Jul 2011Est. completion: May 2015
Phase 1/2Completed
NCT06592859GenomicsNMN

Quzhou Population Cohort Research Project (Aging Related Research: Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People)

Start: Aug 2023Est. completion: Dec 2026240 patients
N/ARecruiting
NCT05377411Soterix MedicaltDCS

SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults

Start: Jan 2023Est. completion: Jun 2024
N/ACompleted
NCT05732909Novo NordiskD-β-hydroxybutyrate/D 1,3 butanediol monoester

The Metabolic Effects of β-hydroxybutyrate on Working Skeletal Muscle

Start: Dec 2022Est. completion: Jan 202425 patients
N/ACompleted
NCT05468905City TherapeuticsNone of intervention

China Longitudinal Aging and Cognitive Impairment Study

Start: Jan 2021Est. completion: Dec 2026
N/ARecruiting
NCT03342729City TherapeuticsIntervention

Aging Mastery Program® (AMP) Evaluation

Start: May 2017Est. completion: Mar 2018
N/ACompleted
NCT02803554Ambrosia BiosciencesPlasma

Young Donor Plasma Transfusion and Age-Related Biomarkers

Start: Jun 2016Est. completion: Jan 2018
N/ACompleted
NCT01256840Johnson & JohnsonLong-term Caloric Restriction and Cellular Aging Markers

Long-term Caloric Restriction and Cellular Aging Markers

Start: Dec 2010Est. completion: Aug 201471 patients
N/ACompleted
NCT00328055PfizerAD-Easy

Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive

Start: Aug 2004Est. completion: Jul 2005200 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 972 patients
13 companies competing in this space