Aytu BioPharma(AYTU)

Focus: Aytu BioPharma is a Denver-based public company operating in diagnostics and small molecules across gastroenterology, infectious diseases, and oncology. The company manages a portfolio of established branded drugs at peak lifecycle alongside early-stage diagnostic and specialty pharma programs.

Gastroenterology Infectious Diseases Oncology

Profile data last refreshed 2h ago · AI intelligence enriched 2w ago

Funding Stage

PUBLIC

Open Jobs

About Aytu BioPharma

AI assessmentNot Hiring

No open roles listed right now. Follow Aytu BioPharma to get notified when they start hiring — the background below is worth knowing for when they do.

Why Work Here

Data completeness

5/9 — Partial

Company HealthStrong

Pipeline

Mid-stage

1 Phase 3+

LOE Risk

1 in 5yr

KARBINAL ER

Hiring

0 open

Revenue

$65M

FY2025

Key Products

ACIPHEX SPRINKLE

Gastroenterology (proton-pump inhibitor)

Peak

Lead branded product at peak lifecycle; proton-pump inhibitor for gastric acid suppression in parietal cells.

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Public company status provides equity exposure and career stability absent in pre-revenue biotech.
Diversified portfolio across small molecules and diagnostics offers cross-functional learning opportunities.
Established cash position of $20M supports continued operations and program advancement.

Watch Out For

Declining revenue (FY 2025: $65M vs FY 2024: $107M, -39% YoY) signals market headwinds and potential restructuring risk.
Consistent net losses ($-15.8M in FY 2025, $-17.1M in FY 2024) despite low R&D spend (4%) raises profitability concerns.
Zero active job openings and minimal R&D intensity (4%) indicate limited hiring velocity and innovation investment.
Portfolio heavily weighted to mature/generic drugs (Aciphex, Zolpimist) with limited clinical catalysts—only 1 Phase 3 program.

Generated by Claude from Aytu BioPharma's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

Sedative hypnotic at peak sales; patent protection extends to August 2032, providing 6+ years of exclusivity runway.

METADATE CD

Attention Deficit Hyperactivity Disorder

LOE Approaching

ADHD treatment approaching loss of exclusivity; revenue erosion expected as generic competition intensifies.

KARBINAL ER

Allergic conditions (H1 receptor antagonist)

LOE Approaching2.6yr

Extended-release antihistamine with patent cliff in March 2029; portfolio diversification into allergy/antihistamine space.

Pipeline & Clinical Trials

ProxiScan

Prostate Cancer

N/A

Clinical Trials (1)

NCT02786459Detection and Localization of Carcinoma Using High Resolution Transrectal Imaging - Proof of Concept Study

N/A

Antioxidant

Compare the sORP Rate in Sperm Samples, Obtained by the Mioxsys System, Before and After 2.5 Months Antioxidant Men Supplements Treatment (Fertybiotic Man)

N/A

Clinical Trials (1)

NCT04758260Influence of the Antioxidant Treatment in the Oxidant-reduction Potential in Seminal Plasma in Men Whose Partners Will Undergo Through an Egg Donation Cycle

N/A

UV Light Treatment

Coronavirus

N/A

Clinical Trials (1)

NCT04572399UVA Light Device to Treat COVID-19

N/A

UVA Light Emitting Catheter

COVID-19 Pneumonia

N/A

Clinical Trials (1)

NCT05166915Respiratory COVID-19: A Randomized, Sham-Controlled Study

N/A

Diagnostic

Male Infertility

N/A

Clinical Trials (1)

NCT02839447A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0

N/A

enzastaurin

Vascular Ehlers-Danlos Syndrome

Phase 3

Clinical Trials (1)

NCT05463679Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome.

Phase 3

ADZENYS XR-ODT

Attention Deficit Hyperactivity Disorder

Phase 4

Clinical Trials (1)

NCT07169162ADZENYS XR-ODT™ in Children (4 to <6 Years) Diagnosed With Attention-deficit/Hyperactivity Disorder

Phase 4

amphetamine extended-release orally disintegrating tablet

Attention Deficit Hyperactivity Disorder

Phase 4

Open Jobs (0)

No open positions listed yet. Check their careers page directly.

Interview Prep Quick Facts

Portfolio: 4 approved products, 7 clinical trials

Top TAs: Oncology, Gastroenterology, Psychiatry

SEC Filings: 2 available

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Portfolio Health

Peak2 (50%)

LOE Approaching2 (50%)

4 total products

Therapeutic Area Focus

1 marketed1 pipeline

1 marketed

1 marketed

1 pipeline

1 pipeline

Financials (FY2025)

Revenue

$65M39%

R&D Spend

$3M(4%)32%

Net Income

-$16M

Aytu BioPharma(AYTU)

About Aytu BioPharma

Why Work Here

Key Products

Watch Out For

Products & Portfolio (2)

Pipeline & Clinical Trials

Recent News · Aytu BioPharma(10)

Open Jobs (0)

Financials (FY2025)