aTyr Pharma(ATYR)

Focus: aTyr Pharma is a public-stage therapeutic protein company focused on respiratory and infectious disease treatments, currently in early-to-mid stage clinical development with minimal revenue generation.

Respiratory Infectious Diseases

Profile data last refreshed 19h ago · AI intelligence enriched 2w ago

Funding Stage

PUBLIC

Open Jobs

About aTyr Pharma

AI assessmentNot Hiring

No open roles listed right now. Follow aTyr Pharma to get notified when they start hiring — the background below is worth knowing for when they do.

Why Work Here

Data completeness

4/9 — Basic

Company HealthStrong

Pipeline

Mid-stage

1 Phase 3+

LOE Risk

Protected

No near-term cliffs

Hiring

0 open

Revenue

$353K

Pipeline & Clinical Trials

A Multicenter Collaborative Study on the Clinical Features, Expression Profiling, and Quality of Lif

Facioscapulohumeral Muscular Dystrophy

N/A

Clinical Trials (1)

NCT01437345A Multicenter Collaborative Study on the Clinical Features, Expression Profiling, and Quality of Life of Infantile Onset FSHD

N/A

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Pioneering therapeutic protein platform with multiple programs spanning high-need areas (muscular dystrophy, pulmonary sarcoidosis, COVID-19 pneumonia)
Public company status provides liquidity and resources, with $23M cash position and focused R&D spend of $42M annually
Early-stage programs offer opportunity to shape clinical development and contribute to potentially transformative rare disease therapies

Watch Out For

Severe cash burn ($50.4M net loss in FY 2025) against only $353K revenue signals 18-24 month runway without additional financing
No active job openings and minimal headcount data suggest company is in conservation mode, limiting near-term hiring and career growth opportunities
Pipeline concentrated in Phase 1/2 programs with only one Phase 3 trial; significant clinical risk and extended path to commercialization

Generated by Claude from aTyr Pharma's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

ATYR1940

Facioscapulohumeral Muscular Dystrophy

PHASE_1_2

Clinical Trials (1)

NCT02531217Safety, Tolerability, Pharmacokinetics (PK), and Activity of ATYR1940 in Participants With Muscular Dystrophy - Study Extension

Phase 1/2

ATYR1940

Facioscapulohumeral Muscular Dystrophy (FSHD)

PHASE_1_2

Clinical Trials (1)

NCT02603562Evaluate Safety and Biological Activity of ATYR1940 in Participants With Early Onset Facioscapulohumeral Muscular Dystrophy

Phase 1/2

ATYR1940

Limb-Girdle Muscular Dystrophies

PHASE_1_2

Clinical Trials (1)

NCT02579239Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Facioscapulohumeral Muscular Dystrophy (FSHD)

Phase 1/2

Efzofitimod 1.0 mg/kg or Placebo

Pulmonary Sarcoidosis

PHASE_1_2

Clinical Trials (1)

NCT03824392Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis

Phase 1/2

ATYR1940

Facioscapulohumeral Muscular Dystrophy

PHASE_1_2

Clinical Trials (1)

NCT02836418Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Participants With Limb Girdle and Facioscapulohumeral Muscular Dystrophy (FSHD)

Phase 1/2

Placebo

Facioscapulohumeral Muscular Dystrophy (FSHD)

PHASE_1_2

Clinical Trials (1)

NCT02239224Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Participants With Muscular Dystrophy

Phase 1/2

efzofitimod 450 mg

Interstitial Lung Disease

PHASE_2

Clinical Trials (1)

NCT05892614Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

Phase 2

Efzofitimod 1 mg/kg

SARS-CoV-2 (COVID-19) Severe Pneumonia

PHASE_2

Clinical Trials (1)

NCT04412668Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19

Phase 2

Efzofitimod 3 mg/kg

Pulmonary Sarcoidosis

PHASE_3

Clinical Trials (1)

NCT05415137Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis

Phase 3

Open Jobs (0)

No open positions listed yet. Check their careers page directly.

Interview Prep Quick Facts

Portfolio: 10 clinical trials

Top TAs: Respiratory, Infectious Diseases

Publications: 24 in PubMed

SEC Filings: 2 available

Therapeutic Area Focus

Respiratory

3 pipeline

Infectious Diseases

1 pipeline

Marketed

Pipeline

Financials (FY2025)

Revenue

$353K97%

R&D Spend

$42M(11981%)1%

Net Income

-$50M

Research Publications(10)

Recent peer-reviewed publications with author affiliations at this company

A bispecific antibody designed to act as a NRP2/PLXNA1 agonist mimics anticancer activity of SEMA3F.

The Journal of biological chemistry

2026

PMID:41391772

A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis.

Science translational medicine

Showing 5 of 10 publications

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aTyr Pharma(ATYR)

About aTyr Pharma

Why Work Here

Pipeline & Clinical Trials

Watch Out For

Recent News · aTyr Pharma(1)

Open Jobs (0)

Financials (FY2025)

Research Publications(10)