NDAORALTABLET, ORALLY DISINTEGRATING
Approved
Feb 2001
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
3/8 — Basic
ZOMIG-ZMT (zolmitriptan) by AstraZeneca is serotonin 1b receptor agonists [moa]. First approved in 2001.
Drug data last refreshed 38m ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZOMIG-ZMT is an orally disintegrating tablet formulation of zolmitriptan, a serotonin 1B receptor agonist (triptan) approved in 2001. It is indicated for acute treatment of migraine headaches with or without aura. The drug works by constricting blood vessels around the brain and reducing substances in the body that can trigger headaches, nausea, sensitivity to light and sound, and other migraine symptoms.
LOE Approaching
With LOE approaching and moderate competitive pressure (30/100), this brand faces revenue contraction; commercial teams should expect portfolio optimization discussions and potential redeployment.
Mechanism of Action
Serotonin 1b Receptor Agonists
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
Determine Central 5-HT1B Receptor Occupancy of ZOMIG® Rapimelt (Zolmitriptan) in Healthy Male Volunteers
Started May 2010
10 enrolled
Migraine
Efficacy and Tolerability of Zolmitriptan Nasal Spray
Started Sep 2002
2,114 enrolled
Migraine
Career Relevance
Working on ZOMIG-ZMT during its LOE phase offers experience in portfolio defense, market-share protection, and legacy-brand optimization—valuable skills in mature-market management. However, career growth is constrained by limited headcount needs and declining investment; this role suits professionals seeking to consolidate expertise rather than launch new initiatives.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.