NDAOPHTHALMICSOLUTION/DROPSPriority Review
Approved
Jun 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
6/8 — Strong
Priority Review
XALATAN (latanoprost) by Viatris (2) is 2α analogue that is believed to reduce the iop by increasing the outflow of aqueous humor. Approved for ocular hypertension, open-angle glaucoma, glaucoma. First approved in 1996.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
XALATAN (latanoprost) is a prostaglandin F2α analog ophthalmic solution that reduces intraocular pressure (IOP) by increasing uveoscleral outflow of aqueous humor. It is indicated for open-angle glaucoma and ocular hypertension, conditions where elevated IOP is a major risk factor for optic nerve damage and visual field loss. Administered as daily eye drops, latanoprost is a foundational therapy in IOP management.
$0.005BPart D
LOE ApproachingDeclining
Product approaching loss of exclusivity; commercial teams likely focused on lifecycle extensions, authorized generics, or transition support rather than growth initiatives.
Mechanism of Action
2α analogue that is believed to reduce the IOP by increasing the outflow of aqueous humor. Studies in animals and man suggest that the main mechanism of action is increased uveoscleral outflow. Elevated IOP represents a major risk factor for glaucomatous field loss. The higher the level of IOP, the…
Pharmacologic Class:
Prostaglandin Analog
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.