NDAORALBAR, CHEWABLE
Approved
Apr 2019
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
12
Data completeness
4/8 — Partial
WELCHOL (colesevelam hydrochloride) by Ichnos Glenmark Innovation is hyperlipidemia: colesevelam hydrochloride, the active pharmaceutical ingredient in colesevelam hydrochloride tablets, is a non-absorbed, lipid-lowering polymer that binds bile acids in the intestine, impeding their reabsorption. Approved for type 2 diabetes, hypercholesterolemia, familial hypercholesterolemia. First approved in 2019.
Drug data last refreshed 20h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
WELCHOL is an oral, non-absorbed bile acid sequestrant polymer approved for treating type 2 diabetes and hypercholesterolemia. It binds bile acids in the intestine to increase LDL clearance and improve glycemic control through mechanisms not fully understood. The drug is available as a chewable bar formulation.
Peak
WELCHOL is in peak lifecycle stage with moderate competitive pressure (30/100), positioning it as a stable franchise requiring ongoing commercial execution and market defense.
Mechanism of Action
Hyperlipidemia: Colesevelam hydrochloride, the active pharmaceutical ingredient in colesevelam hydrochloride tablets, is a non-absorbed, lipid-lowering polymer that binds bile acids in the intestine, impeding their reabsorption. As the bile acid pool becomes depleted, the hepatic enzyme,…
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.