Hypercholesterolemia
Pipeline by Development Stage
Drug Modality Breakdown
On Market (3)
Approved therapies currently available
Competitive Landscape
49 companies ranked by most advanced pipeline stage
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Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 14,948 patients across 50 trials
A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.
Long-term Comparison of Pitavastatin/Ezetimibe and Pitavastatin in Patients With Hypercholesterolemia and Elevated Triglycerides
Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia
Rosuvastatin Effect on Atherosclerotic Plaque Metabolism
Long Term Safety Study of PRALUENT
Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia
Clinical Trial to to Compare of the Efficacy and Safety of Lipilou® 20 mg and Lipilou® 10 mg
Alirocumab in Patients With Acute Myocardial Infarction
Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia
Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo
Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension
Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)
Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS)
Atorvastatin Versus Vitamin E in Treatment of Non-alcoholic Fatty Liver Disease
The HDL Particle Protection Study
Rosuvastatin Effect on Serial Echocardiographic Measurement of Coronary Flow Velocity Reserve
A Study Comparing CoQ10 Levels While Taking 3 Different Statins
Intensive Statin Treatment for STEMI Patients Undergoing Primary PCI
Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemia
Korean AMADEUS Study
Atorvastatin Pre-Treatment Study In Asian Patients With Acute Coronary Syndrome
The Use of Statins for Myocardial Death Prevention
Bioequivalence Study Comparing A New 80 Mg Atorvastatin Tablet To A 80 Mg Atorvastatin Commercial Tablet
Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial Tablet
A Diabetes Study to Treat A Population Previously Not at Target
Safety and Efficacy Study of Pitavastatin in Patient With a Metabolic Syndrome
Virtual Histology Findings and Effects of Varying Doses of Atorvastatin Treatment
Statin Therapy for Ischemic and Nonischemic Cardiomyopathy
Does Atorvastatin Reduce Ischemia-Reperfusion Injury in Humans in-Vivo?
Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients
ROMEO (Rosuvastatin in Metabolic syndrOme)
Irbesartan in Chinese Hypertensive Diabetics With Microalbuminuria
I PREVENT - Irbesartan In Hypertensive Diabetic Patients
Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions
Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)
Irbesartan in the Treatment of Hypertensive Patients With Metabolic Syndrome
Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol
Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart Disease
C-Reactive Protein (CRP) in Obese Diabetic Women
Korean Rosuvastatin Effectiveness Study in Nondiabetic Metabolic Syndrome
Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients
APROVE : Irbesartan in Hypertension
Left Ventricular Function After Acute Myocardial Infarction (AMI). Treatment With Angiotensin 2-Receptor Blockade (GLOBAL-Study)
Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesterol
Irbesartan, Ciprofibrate and Their Combination Onto the Endothelial Functions
Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation
Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)
AMISH : Aprovel for Management of Isolated Systolic Hypertension
A Study Of The Efficacy Of Atorvastatin In Lowering Cholesterol In Latin American Patients With High Cholesterol
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The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.