VENCLEXTA

Peak

venetoclax

NDAORALTABLETPriority Review
Approved
Apr 2016
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

P-Glycoprotein Inhibitors

Pharmacologic Class:

BCL-2 Inhibitor

Clinical Trials (5)

NCT07175415Phase 1/2Not Yet Recruiting

HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Started Oct 2026
42 enrolled
Acute Lymphoblastic LeukemiaLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) RecurrentLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory+2 more
NCT07471841Phase 2Not Yet Recruiting

Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax

Started May 2026
25 enrolled
IDH1 MutationRelapsed / Refractory AML
NCT06782542Phase 2Recruiting

Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy

Started May 2026
16 enrolled
Acute Myeloid LeukemiaIDH1 Mutation
NCT07387471Phase 2Recruiting

Study to Assess Change in Disease Activity of Oral Venetoclax in Adult Participants With Recurring Relapsed or Refractory (R/R) Waldenström Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

Started Mar 2026
14 enrolled
Waldenstrom MacroglobulinemiaLymphoplasmacytic Lymphoma
NCT06510309Phase 2Recruiting

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

Started Feb 2026
33 enrolled
LymphomaMarginal Zone LymphomaMZL

Loss of Exclusivity

LOE Date
Sep 6, 2033
91 months away
Patent Expiry
Sep 6, 2033
Exclusivity Expiry
May 15, 2026

Patent Records (5)

Patent #ExpiryTypeUse Code
9174982
May 26, 2030
U-2323
8546399
Jun 27, 2031
SubstanceProduct
10730873
Nov 21, 2031
Substance
8722657
Jan 29, 2032
Substance
11369599
May 23, 2032
Product