NDATOPICALOINTMENT
Approved
Jan 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
16
Data completeness
4/8 — Partial
VECTICAL (calcitriol) by Galderma is clinical pharmacology man's natural supply of vitamin d depends mainly on exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol in the skin to vitamin d 3 (cholecalciferol). First approved in 2009.
Drug data last refreshed Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VECTICAL is a topical calcitriol (active vitamin D3) ointment indicated for psoriasis and various metabolic bone diseases including secondary hyperparathyroidism and renal osteodystrophy. It works by binding to vitamin D receptors in the intestine and bone to regulate calcium and phosphorus metabolism, mimicking the body's natural active vitamin D hormone. The drug is particularly valuable for patients with chronic kidney disease who cannot adequately synthesize calcitriol endogenously.
$2MPart D
LOE ApproachingVECTICAL operates in a niche therapeutic area with minimal Part D spend ($2M) and declining patent protection, signaling a small, mature brand team focused on maintenance rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Man's natural supply of vitamin D depends mainly on exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol in the skin to vitamin D 3 (cholecalciferol). Vitamin D 3 must be metabolically activated in the liver and the kidney before it is fully…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.