NDAORALTABLET
Approved
Nov 1963
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
7
Data completeness
5/8 — Partial
VALIUM (diazepam) by Viatris (2) is mechanism of action although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with γ-aminobutyric acid (gaba) receptors of the a-type (gaba a ). Approved for epilepsy, alcohol withdrawal, seizures. First approved in 1963.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Valium (diazepam) is a benzodiazepine small molecule that enhances GABA-A receptor signaling to suppress neuronal depolarization and prevent seizures. Approved in 1963, it treats epilepsy, seizures, and alcohol withdrawal by increasing chloride ion influx into neurons. It is one of the most established CNS depressants in pharmaceutical history.
$0.279MPart D
LOE ApproachingDeclining
Product is in mature/declining phase with minimal Part D spending; legacy brand team likely operating in cost-containment and lifecycle extension mode rather than growth investment.
Mechanism of Action
Mechanism of Action Although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with γ-aminobutyric acid (GABA) receptors of the A-type (GABA A ). GABA, the major…
Pharmacologic Class:
Benzodiazepine
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.