NDAINTRAVENOUSSOLUTION
Approved
Dec 2012
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug data last refreshed 17h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Topotecan hydrochloride is a small-molecule topoisomerase I inhibitor administered intravenously as a sterile solution. It is indicated for treatment of various solid tumors including ovarian cancer, small cell lung cancer, and cervical cancer. The drug works by inhibiting topoisomerase I, leading to DNA damage and cell death in rapidly dividing cancer cells.
Peak
Product is at peak lifecycle stage with moderate competitive pressure (30%), suggesting stable revenue and established commercial operations; team size likely optimized but not expanding.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas
Started Mar 2015
178 enrolled
Adult LiposarcomaMetastatic LiposarcomaMetastatic Osteosarcoma+4 more
Career Relevance
Limited linked job count (0) reflects mature product stage and smaller team footprint typical of established generic/authorized generic IV chemotherapies. Career opportunities focus on maximizing existing market share rather than launch activities, with roles concentrated in commercial, medical affairs, and oncology specialty functions.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.