THALITONE (chlorthalidone) by Monarch Therapeutics is clinical pharmacology: chlorthalidone is an oral diuretic with prolonged action (48–72 hours) and low toxicity. Approved for the management of hypertension either, to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension, pregnancy and 6 more indications. First approved in 2005.
Drug data last refreshed 1w ago
CLINICAL PHARMACOLOGY: Chlorthalidone is an oral diuretic with prolonged action (48–72 hours) and low toxicity. The major portion of the drug is excreted unchanged by the kidneys. The diuretic effect of the drug occurs in approximately 2.6 hours and continues for up to 72 hours. The mean half-life…
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Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control
Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control
S-amlodipine+Chlorthalidone vs S-amlodipine+Telmisartan in Hypertension
A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone
Study to Evaluate the Efficacy and Safety of the Combination of Valturna and Amlodipine or Valturna and Chlorthalidone Versus Valturna Alone in Patients With Stage 2 Hypertension and Diabetes