Pregnancy

Pipeline Programs

Companies

Clinical Trials

8 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule

375%

Vaccine

125%

+ 110 programs with unclassified modality

Competitive Landscape

37 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

Human BioSciencesWV - Martinsburg

50 programs

Frequency of IntercoursePhase 41 trial

Quick start oral contraceptive initiationPhase 41 trial

Atmospheric oxygen tensionPhase 31 trial

BetamethasonePhase 31 trial

C31GPhase 31 trial

+45 more programs

Active Trials

NCT00065897Completed6,400Est. Aug 2000

NCT01579617Completed637Est. Dec 2015

NCT03480139Completed746Est. Mar 2023

+42 more trials

Colorado TherapeuticsCO - Louisville

10 programs

Enhanced NFP CarePhase 41 trial

Clomiphene citratePhase 31 trial

LetrozolePhase 3Small Molecule1 trial

Timed intercoursePhase 31 trial

CholinePhase 11 trial

+5 more programs

Active Trials

NCT02219399Completed871Est. Jan 2014

NCT02391519Recruiting84Est. Dec 2026

NCT02391870Completed49Est. Mar 2011

+7 more trials

Angeles Therapeutics

6 programs

Buccal MisoprostolPhase 41 trial

AIM 4 Teen MomsN/A1 trial

CenteringPregnancyN/A1 trial

Pregnant women under investigation for Coronavirus or diagnosed with COVID-19N/A1 trial

SEI Classroom CurriculumN/A1 trial

+1 more programs

Active Trials

NCT01456091Completed954Est. Jan 2016

NCT02640638Completed2,350Est. Jan 2021

NCT04323839Completed1,333Est. Apr 2022

+3 more trials

Oregon Therapeutics

4 programs

Enhanced NFP CarePhase 4

Role of Liver and Visceral Fat in Glucose and Lipid Metabolism During PregnancyN/A1 trial

The Physical Effects of Pain Catastrophizing in LaborN/A1 trial

Use of Computerized Decision Aid on ChildbirthN/A1 trial

Active Trials

NCT02282475Completed78Est. Dec 2018

NCT01012466Completed91Est. Jun 2010

NCT00267735Completed131Est. Oct 2014

DuchesnayQC - Blainville

1 program

Pregvit®Phase 41 trial

Active Trials

NCT02300155Completed1,370Est. Jan 2008

Alliance PharmaceuticalsUK - Wiltshire

2 programs

Docosa Hexaenoic AcidPhase 31 trial

Zambian Preterm Birth Prevention StudyN/A1 trial

Active Trials

NCT02738892Active Not Recruiting9,000Est. Oct 2026

NCT03072277Completed957Est. Dec 2020

Juniper Biosciences

1 program

8% progesterone vaginal gelPhase 31 trial

Active Trials

NCT00086177Completed636Est. Mar 2009

Allergy TherapeuticsUK - West Sussex

2 programs

DPPPhase 21 trial

CeftriaxonN/A5 trials

Active Trials

NCT07207876Recruiting110Est. May 2027

NCT03840811Completed27Est. Nov 2019

NCT02210325Completed264Est. Feb 2017

+3 more trials

Temple TherapeuticsNetherlands - Geleen

2 programs

Healthy Lifestyle GroupPhase 21 trial

Healthy Lifestyle GroupN/A1 trial

Active Trials

NCT02229708Completed262Est. Jul 2019

NCT01530776Completed66Est. Mar 2016

PharmacosmosDenmark - Holbaek

1 program

Intravaneous ironPhase 21 trial

Active Trials

NCT02038023Completed74Est. Aug 2015

Merck & Co.RAHWAY, NJ

4 programs

Correlation Between PIF Maternal Serum Levels and Pregnancy OutcomeN/A1 trial

Placental Passage and Disposition of Drugs: A Physiology-based ApproachN/A

Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy OutcomeN/A1 trial

300IU rec-LHPHASE_41 trial

Active Trials

NCT01805102Unknown500

NCT01803893Unknown500

NCT00954811Unknown40Est. Dec 2010

AstraZenecaCAMBRIDGE, United Kingdom

2 programs

A Non-interventional Multi-country Cohort Study to Assess the Safety of EVUSHELD™ During PregnancyN/A1 trial

The National Register of Antipsychotic Medication in Pregnancy (NRAMP)N/A1 trial

Active Trials

NCT05847140Withdrawn0Est. Jan 2024

NCT00686946Unknown500Est. Dec 2025

iNova PharmaceuticalsAustralia - Chatswood

2 programs

Blood sugar check every 2 hoursN/A1 trial

Subcuticular monocryl sutureN/A1 trial

Active Trials

NCT05647798Terminated2Est. May 2024

NCT07167199Not Yet Recruiting237Est. Sep 2027

GE HealthCare

2 programs

Fetal Monitoring DeviceN/A1 trial

Investigational Fetal MonitorN/A1 trial

Active Trials

NCT06726343Completed30Est. Dec 2024

NCT06835647Recruiting15Est. Dec 2025

Genome & Company

2 programs

Invasive Prenatal Testing Decisions in Pregnancy After InfertilityN/A

Prevalence of Ambivalence Regarding Prenatal TestingN/A

PfizerNEW YORK, NY

2 programs

MRSA Colonization in Peripartum Women and Their OffspringN/A1 trial

The National Register of Antipsychotic Medication in Pregnancy (NRAMP)N/A

Active Trials

NCT00336427Completed600Est. May 2006

AstellasChina - Shenyang

1 program

Amevive exposureN/A1 trial

Active Trials

NCT00342862Terminated3Est. Dec 2011

Rivanna MedicalVA - Charlottesville

1 program

Control groupN/A1 trial

Active Trials

NCT02442973Completed130Est. Jan 2018

Affinia Therapeutics

1 program

INVU fetal monitoring systemN/A1 trial

Active Trials

NCT06741735Recruiting150Est. Jul 2027

UNION therapeuticsDenmark - Hellerup

1 program

Maternal Gestational Weight Gain and Microbiota of Maternal and InfantN/A1 trial

Active Trials

NCT03916354Unknown550Est. Dec 2021

BayerLEVERKUSEN, Germany

1 program

MirenaN/A1 trial

Active Trials

NCT02414919Completed13,880Est. Mar 2016

Integrated Biosciences

1 program

NIPTN/A1 trial

Active Trials

NCT04595201Recruiting25,000Est. Oct 2025

Guard Therapeutics

1 program

Outcome of Pregnancy and Breast CancerN/A1 trial

Active Trials

NCT02774915Unknown20Est. Nov 2019

March Biosciences

1 program

PLAC1 in ReproductionN/A1 trial

Active Trials

NCT01277848Completed500Est. May 2015

MSDIreland - Ballydine

1 program

Placental Passage and Disposition of Drugs: A Physiology-based ApproachN/A1 trial

Active Trials

NCT02438631Recruiting2,000Est. Dec 2028

Sharp TherapeuticsPA - Pittsburgh

1 program

Placental Passage and Disposition of Drugs: A Physiology-based ApproachN/A

One Biosciences

1 program

Pregnancies Complicated by Fetal AnomaliesN/A1 trial

Active Trials

NCT02505464RecruitingEst. Apr 2028

SanofiPARIS, France

1 program

Quadrivalent Intradermal Influenza VaccineN/AVaccine1 trial

Active Trials

NCT02554409Completed87Est. Apr 2019

Innovation PharmaceuticalsMA - Wakefield

1 program

Teen Options to Prevent PregnancyN/A1 trial

Active Trials

NCT01456793Completed598Est. Sep 2016

Cumberland PharmaceuticalsTN - Nashville

1 program

VIBATIVN/A1 trial

Active Trials

NCT01130324Withdrawn0Est. Oct 2020

+7 more companies

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

2028

2029

2030

2031

Angeles TherapeuticsBuccal Misoprostol

Colorado TherapeuticsEnhanced NFP Care

Human BioSciencesFrequency of Intercourse

Merck & Co.300IU rec-LH

DuchesnayPregvit®

Human BioSciencesQuick start oral contraceptive initiation

Alliance PharmaceuticalsDocosa Hexaenoic Acid

Allergy TherapeuticsCeftriaxon

Human BioSciencesBetamethasone

Colorado TherapeuticsLetrozole

Colorado TherapeuticsTimed intercourse

Human BioSciencesAtmospheric oxygen tension

Colorado TherapeuticsClomiphene citrate

Human BioSciencesDHA

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 59,682 patients across 50 trials

NCT01519765 Angeles TherapeuticsBuccal Misoprostol

Buccal Versus Vaginal Misoprostol for Third Trimester Induction of Labor

Start: Jul 2011Est. completion: Dec 201473 patients

Phase 4Terminated

NCT00928538 Colorado TherapeuticsEnhanced NFP Care

Nurse Family Partnership (NFP) Contraceptive Study

Start: Sep 2009Est. completion: May 2015344 patients

Phase 4Completed

NCT00740506 Human BioSciencesFrequency of Intercourse

Behavioral and Environmetal Factors and Time to Delivery

Start: Aug 2008Est. completion: Jul 2009510 patients

Phase 4Completed

NCT00954811 Merck & Co.300IU rec-LH

Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)

Start: Sep 2005Est. completion: Dec 201040 patients

Phase 4Unknown

NCT02300155 DuchesnayPregvit®

Improving Multivitamin Supplementation to Pregnant Women

Start: Oct 2004Est. completion: Jan 20081,370 patients

Phase 4Completed

NCT00068848 Human BioSciencesQuick start oral contraceptive initiation

Quick Start Approach to Birth Control Pills

Start: Feb 2003Est. completion: Mar 20052,000 patients

Phase 4Completed

NCT03072277 Alliance PharmaceuticalsDocosa Hexaenoic Acid

Maternal DHA Supplementation and Offspring Neurodevelopment in India (DHANI-2)

Start: Dec 2015Est. completion: Dec 2020957 patients

Phase 3Completed

NCT02210325 Allergy TherapeuticsCeftriaxon

Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea

Start: Aug 2014Est. completion: Feb 2017264 patients

Phase 3Completed

NCT01222247 Human BioSciencesBetamethasone

Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial

Start: Oct 2010Est. completion: Aug 20222,831 patients

Phase 3Completed

NCT01044862 Colorado TherapeuticsLetrozole

Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation

Start: Jun 2010Est. completion: Mar 2014900 patients

Phase 3Completed

NCT00767338 Colorado TherapeuticsTimed intercourse

Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis

Start: May 2010Est. completion: Nov 20113 patients

Phase 3Terminated

NCT01010386 Human BioSciencesAtmospheric oxygen tension

The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes

Start: Mar 2010Est. completion: Feb 2014851 patients

Phase 3Completed

NCT00719186 Colorado TherapeuticsClomiphene citrate

Pregnancy in Polycystic Ovary Syndrome II

Start: Feb 2009Est. completion: May 2013750 patients

Phase 3Completed

NCT02487771 Human BioSciencesDHA

Kansas University DHA Outcome Study (KUDOS) Follow-Up

Start: Jul 2008Est. completion: May 2016190 patients

Phase 3Completed

NCT00266825 Human BioSciencesDHA

DHA Supplementation and Pregnancy Outcome

Start: Jan 2006Est. completion: Oct 2011350 patients

Phase 3Completed

NCT00274261 Human BioSciencesC31G

Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®

Start: Jun 2004Est. completion: Sep 20081,565 patients

Phase 3Completed

NCT00086177 Juniper Biosciences8% progesterone vaginal gel

Vaginal Progesterone to Reduce the Risk of Another Preterm Birth

Start: Apr 2004Est. completion: Mar 2009636 patients

Phase 3Completed

NCT00098709 Human BioSciencesFetal pulse oximeter

Fetal Pulse Oximetry Trial (FOX)

Start: May 2002Est. completion: Feb 200510,000 patients

Phase 3Terminated

NCT00065858 Human BioSciencesBufferGel

Effectiveness of BufferGel as a Vaginal Contraceptive

Start: Sep 2001Est. completion: Apr 2005975 patients

Phase 2/3Completed

NCT07288190 Allergy TherapeuticsDPP

Phase 2b, Open Label, Multisite, Randomized Crossover Study of DPP Versus 2PR

Start: May 2026Est. completion: May 2028300 patients

Phase 2Not Yet Recruiting

NCT02038023 PharmacosmosIntravaneous iron

Intravaneous Iron(1000 mg Low Molecular Weight Iron Dextran Over 60 Minutes) for Pregnant Women

Start: Jul 2013Est. completion: Aug 201574 patients

Phase 2Completed

NCT01530776 Temple TherapeuticsHealthy Lifestyle Group

Healthy4Baby: Preventing Postpartum Weight Retention Among Low-Income, Black Women

Start: Jan 2012Est. completion: Mar 201666 patients

Phase 2Completed

NCT00710242 DilaforDF01

Study to Assess Safety and Efficacy of DF01 in Reducing Prolonged Labor

Start: Apr 2007Est. completion: May 2009263 patients

Phase 2Completed

NCT00409825 Human BioSciences17-OHPC

Study of Pharmacology of 17-OHPC in Pregnancy

Start: Mar 2006Est. completion: Feb 201461 patients

Phase 2Completed

NCT05452174 Human BioSciencesMirtazapine

Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP)

Start: Jun 2022Est. completion: Oct 20230

Phase 1/2Withdrawn

NCT03840811 Allergy TherapeuticsCeftriaxon

Experimental Human Infection With Neisseria Gonorrhoeae

Start: Apr 2017Est. completion: Nov 201927 patients

Phase 1Completed

NCT02817464 TevaTV-46046 - 400 mg/mL

Study to Evaluate Suppression of Ovulation and Pharmacokinetics of Medroxyprogesterone Acetate Following Administration of TV-46046 in Women With Ovulatory Cycle

Start: Oct 2016Est. completion: Dec 201812 patients

Phase 1Completed

NCT02510534 Ferring PharmaceuticalsMenopur 150 international units

Effect of Luteal Progesterone Support on Pregnancy Rates With Combined Clomid/ Gonadotropin & IUI

Start: Jul 2015Est. completion: Apr 2016520 patients

Phase 1Terminated

NCT04870138 Allergy TherapeuticsCeftriaxon

Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)

Start: Mar 2013Est. completion: Apr 201516 patients

Phase 1Completed

NCT00873886 Human BioSciencesOseltamivir

A Study of the Pharmacology of Oseltamivir (Tamiflu) in Pregnancy

Start: Apr 2009Est. completion: Sep 20100

Phase 1Withdrawn

NCT00332124 Colorado TherapeuticsCholine

Safety and Effectiveness of Taking Choline Supplements During Pregnancy for Improving Infant Brain Development

Start: Jun 2006Est. completion: Mar 2017351 patients

Phase 1Completed

NCT00341640 Human BioSciencesBlood testing

Metabolism of Nicotine and Cotinine in Pregnant African-American Women

Start: Jan 2005Est. completion: Dec 200650 patients

Phase 1Completed

NCT07167199 iNova PharmaceuticalsSubcuticular monocryl suture

Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery

Start: Aug 2026Est. completion: Sep 2027237 patients

N/ANot Yet Recruiting

NCT07213284 Human BioSciencesMI MOM App

Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial

Start: Apr 2026Est. completion: Dec 2031500 patients

N/ANot Yet Recruiting

NCT07207876 Allergy TherapeuticsCeftriaxon

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

Start: Feb 2026Est. completion: May 2027110 patients

N/ARecruiting

NCT07223112 Human BioSciencesSit Less, Move More

Effectiveness of Interventions to Promote Physical Activity During Pregnancy

Start: Feb 2026Est. completion: Aug 202760 patients

N/ARecruiting

NCT06835647 GE HealthCareInvestigational Fetal Monitor

Maternal Fetal Device Performance Twins

Start: Jan 2025Est. completion: Dec 202515 patients

N/ARecruiting

NCT06741735 Affinia TherapeuticsINVU fetal monitoring system

Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

Start: Dec 2024Est. completion: Jul 2027150 patients

N/ARecruiting

NCT06788977 Cefalyexternal Trigeminal Nerve Stimulation

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

Start: Nov 2024Est. completion: Dec 2030550 patients

N/ARecruiting

NCT06726343 GE HealthCareFetal Monitoring Device

Maternal Fetal Device Performance Singleton

Start: Oct 2024Est. completion: Dec 202430 patients

N/ACompleted

NCT05647798 iNova PharmaceuticalsBlood sugar check every 2 hours

Intrapartum Glycemic Control in GDMA2

Start: May 2023Est. completion: May 20242 patients

N/ATerminated

NCT05847140 AstraZenecaA Non-interventional Multi-country Cohort Study to Assess the Safety of EVUSHELD™ During Pregnancy

A Non-interventional Multi-country Cohort Study to Assess the Safety of EVUSHELD™ During Pregnancy

Start: Jun 2022Est. completion: Jan 20240

N/AWithdrawn

NCT05000645 Human BioSciencesGrocery delivery

Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women

Start: Dec 2021Est. completion: Apr 2027570 patients

N/ARecruiting

NCT05035160 Angeles TherapeuticsUCLA Perinatal Biospecimen Repository

UCLA Perinatal Biospecimen Repository

Start: Jul 2021Est. completion: Dec 20281,000 patients

N/ARecruiting

NCT04595201 Integrated BiosciencesNIPT

Clinical Follow-up of Pregnant Subjects Undergoing NIPT

Start: Oct 2020Est. completion: Oct 202525,000 patients

N/ARecruiting

NCT04323839 Angeles TherapeuticsPregnant women under investigation for Coronavirus or diagnosed with COVID-19

COVID-19 PRIORITY (Pregnancy CoRonavIrus Outcomes RegIsTrY)

Start: Mar 2020Est. completion: Apr 20221,333 patients

N/ACompleted

NCT03916354 UNION therapeuticsMaternal Gestational Weight Gain and Microbiota of Maternal and Infant

Maternal Gestational Weight Gain and Microbiota of Maternal and Infant

Start: May 2019Est. completion: Dec 2021550 patients

N/AUnknown

NCT03480139 Human BioSciencesBiomarkers in Obstetrical Complications

Biomarkers in Obstetrical Complications

Start: Feb 2018Est. completion: Mar 2023746 patients

N/ACompleted

NCT02640638 Angeles TherapeuticsCenteringPregnancy

A RCT of CenteringPregnancy on Birth Outcomes

Start: Feb 2016Est. completion: Jan 20212,350 patients

N/ACompleted

NCT02442973 Rivanna MedicalControl group

Handheld 3D Lumbar Spine Navigation: A Clinical Validation Study RM002

Start: Feb 2016Est. completion: Jan 2018130 patients

N/ACompleted

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

14 late-stage (Phase 3) programs, potential near-term approvals

8 actively recruiting trials targeting 59,682 patients

30 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.