Pregnancy

Pipeline Programs

Companies

Clinical Trials

3 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine

1100%

+ 17 programs with unclassified modality

Competitive Landscape

14 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

Merck & Co.RAHWAY, NJ

4 programs

300IU rec-LHPhase 41 trial

Correlation Between PIF Maternal Serum Levels and Pregnancy OutcomeN/A1 trial

Placental Passage and Disposition of Drugs: A Physiology-based ApproachN/A

Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy OutcomeN/A1 trial

Active Trials

NCT01805102Unknown

NCT01803893Unknown

NCT00954811Unknown40Est. Dec 2010

Alliance PharmaceuticalsUK - Wiltshire

2 programs

Docosa Hexaenoic AcidPhase 31 trial

Zambian Preterm Birth Prevention StudyN/A1 trial

Active Trials

NCT02738892Active Not Recruiting9,000Est. Oct 2026

NCT03072277Completed957Est. Dec 2020

DilaforSweden - Solna

1 program

DF01Phase 21 trial

Active Trials

NCT00710242CompletedEst. May 2009

Ferring PharmaceuticalsArgentina - Buenos Aires

1 program

Menopur 150 international unitsPhase 11 trial

Active Trials

NCT02510534Terminated520Est. Apr 2016

TevaIsrael - Petach Tikva

1 program

TV-46046 - 400 mg/mLPhase 11 trial

Active Trials

NCT02817464Completed12Est. Dec 2018

Allergy TherapeuticsUK - West Sussex

1 program

CeftriaxonN/A1 trial

Active Trials

NCT07207876RecruitingEst. Apr 2027

AmgenTHOUSAND OAKS, CA

1 program

EtanerceptN/A1 trial

Active Trials

NCT00116272Completed830Est. Jun 2014

Affinia TherapeuticsMA - Waltham

1 program

INVU fetal monitoring systemN/A1 trial

Active Trials

NCT06741735RecruitingEst. Jul 2027

PfizerNEW YORK, NY

1 program

MRSA Colonization in Peripartum Women and Their OffspringN/A1 trial

Active Trials

NCT00336427Completed600Est. May 2006

One BiosciencesFrance - Paris

1 program

Pregnancies Complicated by Fetal AnomaliesN/A1 trial

Active Trials

NCT02505464RecruitingEst. Apr 2028

SanofiPARIS, France

1 program

Quadrivalent Intradermal Influenza VaccineN/AVaccine1 trial

Active Trials

NCT02554409Completed87Est. Apr 2019

AstraZenecaCAMBRIDGE, United Kingdom

1 program

The National Register of Antipsychotic Medication in Pregnancy (NRAMP)N/A

Catalyst PharmaceuticalsCORAL GABLES, FL

1 program

Wondaleaf®N/A1 trial

Active Trials

NCT02593214CompletedEst. Sep 2016

Amryt PharmaUK - London

1 program

lomitapideN/A1 trial

Active Trials

NCT02399839Terminated5Est. Dec 2022

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

2028

Merck & Co.300IU rec-LH

Alliance PharmaceuticalsDocosa Hexaenoic Acid

DilaforDF01

TevaTV-46046 - 400 mg/mL

Ferring PharmaceuticalsMenopur 150 international units

Allergy TherapeuticsCeftriaxon

Affinia TherapeuticsINVU fetal monitoring system

SanofiQuadrivalent Intradermal Influenza Vaccine

Alliance PharmaceuticalsZambian Preterm Birth Prevention Study

Catalyst PharmaceuticalsWondaleaf®

One BiosciencesPregnancies Complicated by Fetal Anomalies

Amryt Pharmalomitapide

Merck & Co.Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome

Merck & Co.Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome

PfizerMRSA Colonization in Peripartum Women and Their Offspring

Showing 15 of 16 trials with date data

Clinical Trials (16)

Total enrollment: 12,051 patients across 16 trials

NCT00954811 Merck & Co.300IU rec-LH

Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)

Start: Sep 2005Est. completion: Dec 201040 patients

Phase 4Unknown

NCT03072277 Alliance PharmaceuticalsDocosa Hexaenoic Acid

Maternal DHA Supplementation and Offspring Neurodevelopment in India (DHANI-2)

Start: Dec 2015Est. completion: Dec 2020957 patients

Phase 3Completed

NCT00710242 DilaforDF01

Study to Assess Safety and Efficacy of DF01 in Reducing Prolonged Labor

Start: Apr 2007Est. completion: May 2009

Phase 2Completed

NCT02817464 TevaTV-46046 - 400 mg/mL

Study to Evaluate Suppression of Ovulation and Pharmacokinetics of Medroxyprogesterone Acetate Following Administration of TV-46046 in Women With Ovulatory Cycle

Start: Oct 2016Est. completion: Dec 201812 patients

Phase 1Completed

NCT02510534 Ferring PharmaceuticalsMenopur 150 international units

Effect of Luteal Progesterone Support on Pregnancy Rates With Combined Clomid/ Gonadotropin & IUI

Start: Jul 2015Est. completion: Apr 2016520 patients

Phase 1Terminated

NCT07207876 Allergy TherapeuticsCeftriaxon

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

Start: Feb 2026Est. completion: Apr 2027

N/ARecruiting

NCT06741735 Affinia TherapeuticsINVU fetal monitoring system

Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

Start: Dec 2024Est. completion: Jul 2027

N/ARecruiting

NCT02554409 SanofiQuadrivalent Intradermal Influenza Vaccine

Sanofi Pasteur Quadrivalent Intradermal Influenza Vaccine Pregnancy Registry

Start: Oct 2015Est. completion: Apr 201987 patients

N/ACompleted

NCT02738892 Alliance PharmaceuticalsZambian Preterm Birth Prevention Study

Zambian Preterm Birth Prevention Study

Start: Aug 2015Est. completion: Oct 20269,000 patients

N/AActive Not Recruiting

NCT02593214 Catalyst PharmaceuticalsWondaleaf®

Performance and Safety Trial of an Innovative Female Condom (Wondaleaf®)

Start: Aug 2015Est. completion: Sep 2016

N/ACompleted

NCT02505464 One BiosciencesPregnancies Complicated by Fetal Anomalies

Pregnancies Complicated by Fetal Anomalies

Start: May 2015Est. completion: Apr 2028

N/ARecruiting

NCT02399839 Amryt Pharmalomitapide

Global Lomitapide Pregnancy Exposure Registry

Start: Oct 2014Est. completion: Dec 20225 patients

N/ATerminated

NCT01805102 Merck & Co.Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome

Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome

Start: Sep 2012

N/AUnknown

NCT01803893 Merck & Co.Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome

Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome

Start: Sep 2012

N/AUnknown

NCT00336427 PfizerMRSA Colonization in Peripartum Women and Their Offspring

MRSA Colonization in Peripartum Women and Their Offspring

Start: Sep 2005Est. completion: May 2006600 patients

N/ACompleted

NCT00116272 AmgenEtanercept

Organization of Teratology Information Services (OTIS) Autoimmune Diseases in Pregnancy Project

Start: Apr 2005Est. completion: Jun 2014830 patients

N/ACompleted

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals

3 actively recruiting trials targeting 12,051 patients

18 companies competing in this space