TAVNEOS

Peak

avacopan

NDAORALCAPSULE
Approved
Oct 2021
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
10

Mechanism of Action

Complement 5a Receptor Antagonists

Pharmacologic Class:

Complement 5a Receptor Antagonist

Clinical Trials (5)

NCT07176546Phase 2/3Not Yet Recruiting

TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With Polyangiitis

Started Jul 2026
30 enrolled
Granulomatosis With PolyangiitisWegener'sGPA
NCT06321601Phase 3Recruiting

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

Started Oct 2024
20 enrolled
Vasculitis
NCT06468826Phase 1Completed

A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD)

Started Jul 2024
13 enrolled
End-Stage Renal Disease (ESRD)
NCT06072482Phase 4Recruiting

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Started Feb 2024
300 enrolled
Antineutrophil Cytoplasmic Antibody-associated Vasculitis
NCT06207682Phase 1Completed

Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin

Started Jun 2022
32 enrolled
Healthy Volunteers

Loss of Exclusivity

LOE Date
Nov 27, 2039
167 months away
Patent Expiry
Nov 27, 2039
Exclusivity Expiry
Oct 7, 2028

Patent Records (4)

Patent #ExpiryTypeUse Code
8445515
Feb 3, 2031
SubstanceProduct
8906938
Jan 6, 2034
SubstanceProduct
11603356
Nov 27, 2039
SubstanceProduct
U-3558
11951214
Nov 27, 2039
Product