NDATOPICALSUSPENSION
Approved
May 2008
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
4/8 — Partial
TACLONEX (calcipotriene and betamethasone dipropionate) by Leo Pharma is 3 analog and betamethasone dipropionate as a synthetic corticosteroid. First approved in 2008.
Drug data last refreshed 6h ago · AI intelligence enriched 9h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TACLONEX is a fixed-dose topical combination of calcipotriene (a vitamin D3 analog) and betamethasone dipropionate (a synthetic corticosteroid) formulated as a suspension for topical application. It treats plaque psoriasis of the scalp and body by leveraging dual mechanisms: vitamin D analog activity and corticosteroid anti-inflammatory effects. The exact mechanism in psoriasis treatment remains incompletely understood, though both components have established pharmacologic activity in skin disease.
$0.665MPart D
LOE ApproachingProduct is in late-stage lifecycle with modest Medicare Part D claims (~376 annual scripts), signaling a mature brand with contracted commercial infrastructure facing imminent generic competition.
Mechanism of Action
3 analog and betamethasone dipropionate as a synthetic corticosteroid. However, while their pharmacologic and clinical effects are known, the exact mechanisms of their actions in the treatment of plaque psoriasis of the scalp and body are unknown.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (6)
An Observational Study to Assess Patient Satisfaction and Control of Psoriasis With Calcipotriene/Betamethasone Dipropionate (Taclonex®) Topical Suspension, and Effect on Quality of Life
Started Jul 2013
147 enrolled
Psoriasis Vulgaris
A Study to Determine the Efficacy of Taclonex Topical Suspension as a Supplement to Non-biologic Systemic Therapy
Started Jan 2013
8 enrolled
Psoriasis
Patient Preference of Taclonex Ointment to Taclonex Scalp Suspension in Adult Subjects With Psoriasis Vulgaris
Started Oct 2012
20 enrolled
Plaque Psoriasis
Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris
Started Jul 2009
33 enrolled
Psoriasis Vulgaris
Effect of Topical Calcipotriene/Betamethasone (Taclonex) in Managing Localized Breakthrough in Moderate to Severe Plaque Psoriasis in Patients Receiving Efalizumab (Raptiva)
Started Jan 2008
6 enrolled
Plaque Psoriasis
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.