PARLODEL
LOE Approachingbromocriptine mesylate
NDAORALTABLETPriority Review
Approved
Jun 1978
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
CLINICAL PHARMACOLOGY Bromocriptine mesylate is a dopamine receptor agonist, which activates post-synaptic dopamine receptors. The dopaminergic neurons in the tuberoinfundibular process modulate the secretion of prolactin from the anterior pituitary by secreting a prolactin inhibitory factor…
Indications (10)
dysfunctions associated with hyperprolactinemia including amenorrhea withwithout galactorrheainfertilityhypogonadismprolactin-secreting adenomaswhich may be the basic underlying endocrinopathy contributing to the above clinical presentationsthe treatment of acromegalythe treatment of the signssymptoms of idiopathicpostencephalitic Parkinson's disease