OXBRYTA

Peak

voxelotor

NDAORALTABLET, FOR SUSPENSIONPriority Review
Approved
Dec 2021
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
15

Mechanism of Action

Hemoglobin S Polymerization Inhibitors

Pharmacologic Class:

Hemoglobin S Polymerization Inhibitor

Clinical Trials (5)

NCT06023199Phase 2Active Not Recruiting

Assessing Physical Function in Sickle Cell Patients Taking Voxelotor

Started Oct 2023
6 enrolled
Sickle Cell Disease
NCT05228821Phase 4Withdrawn

Voxelotor Brain Oxygenation and Neurocognitive Study

Started Aug 2023
0
Sickle Cell Disease
NCT05981365Phase 1Completed

Voxelotor CYP and Transporter Cocktail Interaction Study

Started Apr 2023
44 enrolled
Sickle Cell Disease
NCT05199766Phase 2Unknown

Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor

Started Mar 2023
30 enrolled
Sickle Cell Disease
NCT05228834Phase 3Terminated

Voxelotor Neurocognitive Function Study

Started Jun 2022
1 enrolled
Sickle Cell Disease

Loss of Exclusivity

LOE Date
Dec 2, 2036
130 months away
Patent Expiry
Dec 2, 2036
Exclusivity Expiry
Dec 17, 2028

Patent Records (5)

Patent #ExpiryTypeUse Code
10034879
Dec 28, 2032
SubstanceProduct
10806733
Dec 28, 2032
Substance
10017491
Dec 28, 2032
Product
9018210
Nov 25, 2033
SubstanceProduct
9248199
Jan 29, 2034
U-2715