NDATOPICALAEROSOL, FOAM
Approved
Jan 2007
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Clinical Trials
14
Data completeness
5/8 — Partial
OLUX E (clobetasol propionate) by R-Pharm US is clinical pharmacology: the corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. Approved for psoriasis, atopic dermatitis, seborrheic dermatitis and 2 more indications. First approved in 2007.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
OLUX E is a topical clobetasol propionate 0.05% foam formulation, a Class I (super-potent) corticosteroid approved in 2007 for inflammatory skin conditions including psoriasis, atopic dermatitis, and seborrheic dermatitis. It works through anti-inflammatory, antipruritic, and vasoconstrictive mechanisms characteristic of corticosteroids, with systemic absorption potential requiring monitoring of HPA axis suppression with prolonged use.
LOE Approaching2.5 years to LOE
Product is in late-stage lifecycle with formulation patent expiring in 2.5 years; brand team focus shifts toward LOE planning and cost containment rather than growth.
Mechanism of Action
CLINICAL PHARMACOLOGY: The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects. Topical…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.