OCREVUS (ocrelizumab) by Roche is cd20-directed antibody interactions [moa]. Approved for multiple sclerosis, relapsing-remitting, primary progressive multiple sclerosis. First approved in 2017.
Drug data last refreshed 6d ago · AI intelligence enriched 2w ago
OCREVUS (ocrelizumab) is a CD20-directed cytolytic monoclonal antibody approved by the FDA on March 28, 2017, developed by Roche. It is indicated for the treatment of multiple sclerosis by targeting CD20+ B cells to reduce inflammation and disease progression. The drug represents a key therapeutic option in the MS market, offering both relapsing and progressive forms of the disease management through B-cell depletion mechanism.
CD20-directed Antibody Interactions
CD20-directed Cytolytic Antibody
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A Study to Evaluate Pharmacokinetics, Safety, Tolerability, Immunogenicity and Pharmacodynamic Effects of Subcutaneous Ocrelizumab Administration in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)
IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)
Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis
People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists
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$157M Medicare spend — this is a commercially significant brand
OCREVUS creates opportunities for brand managers, field medical specialists, account managers, and neurology-focused sales representatives given its MS indication focus. Relevant skills include knowledge of CD20 mechanism of action, MS disease pathology, neurologist engagement strategies, and biosimilar competitive dynamics. Currently zero open positions linked to OCREVUS in available job data, though roles may exist in medical affairs, market access, and specialty pharmacy support functions.