NEXLETOL

Peak

bempedoic acid

NDAORALTABLET
Approved
Feb 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
14

Mechanism of Action

Adenosine Triphosphate-Citrate Lyase Inhibitors

Pharmacologic Class:

Adenosine Triphosphate-Citrate Lyase Inhibitor

Clinical Trials (5)

NCT07440381Phase 3Not Yet Recruiting

triPle Oral thERapy With Bempedoic Acid vs uSual Care in Early Lipid Management of Patients With acUte coronAry synDromE

Started Sep 2026
600 enrolled
Acute Coronary SyndromesSecondary PreventionLipids
NCT07474649Phase 3Not Yet Recruiting

A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events

Started Jun 2026
103 enrolled
Coronary AtherosclerosisMixed DyslipidemiaHypercholesterolemia
NCT07206472N/ANot Yet Recruiting

A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia

Started Jan 2026
2,560 enrolled
Primary HypercholesterolaemiaMixed Dyslipidemia
NCT07268625Phase 1Completed

Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and Atorvastatin

Started Dec 2025
58 enrolled
Healthy Subjects
NCT07235189Phase 1Completed

A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Atorvastatin

Started Oct 2025
58 enrolled
Healthy Subjects

Loss of Exclusivity

LOE Date
Jun 19, 2040
173 months away
Patent Expiry
Jun 19, 2040
Exclusivity Expiry
Mar 22, 2027

Patent Records (5)

Patent #ExpiryTypeUse Code
7335799
Dec 3, 2030
Substance
11744816
Mar 14, 2036
U-3883
11613511
Jun 19, 2040
Substance
12398087
Jun 19, 2040
SubstanceProduct
12404227
Jun 19, 2040
Substance
U-4258