METROGEL

LOE ApproachingSM

metronidazole

NDATOPICALGEL
Approved
Jun 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

12.1 Mechanism of Action The mechanism of action of metronidazole in the treatment of rosacea is unknown. 12.2 Pharmacodynamics The pharmacodynamics of metronidazole in association with the treatment of rosacea are unknown. Cardiac Electrophysiology: The effect of Metronidazole Gel, 1% on the QTc…

Pharmacologic Class:

Nitroimidazole Antimicrobial

Clinical Trials (5)

NCT03830333Phase 3Completed

Ceftolozane/Tazobactam (MK-7625A) Plus Metronidazole Versus Meropenem for Participants With Complicated Intra-abdominal Infection (MK-7625A-015)

Started Mar 2019
268 enrolled
Complicated Intra-abdominal Infections
NCT03329092Phase 3Completed

A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.

Started Apr 2018
422 enrolled
Complicated Intra-abdominal InfectionHosptial Acquired PneumoniaVentilator Associated Pneumonia
NCT03217136Phase 2Completed

MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)

Started Apr 2018
94 enrolled
Complicated Intra-Abdominal Infection
NCT02911298Phase 1Completed

Pharmaco-Scintigraphic Study to Evaluate the Release Profile of Metronidazole Benzoate Capsules

Started Nov 2016
NCT02739997Phase 3Completed

Study of Ceftolozane/Tazobactam (MK-7625A) in Combination With Metronidazole in Japanese Participants With Complicated Intra-abdominal Infection (MK-7625A-013)

Started Apr 2016
100 enrolled
Intra-abdominal InfectionComplicated Intra-abdominal Infection