NDAINJECTIONINJECTABLE
Approved
Aug 1947
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
METHADONE HYDROCHLORIDE (methadone hydrochloride) by Viatris (2) is mechanism of action methadone hydrochloride is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine, the most prominent of which involve the central nervous system and organs composed of smooth muscle. First approved in 1947.
Drug data last refreshed 5d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Methadone hydrochloride is a synthetic mu-opioid agonist approved since 1947 for analgesia and opioid addiction management. It is indicated for HIV infection and candidiasis, though its primary therapeutic uses remain pain management and opioid detoxification/maintenance. The drug acts on central nervous systems and smooth muscle organs, with a slower onset and more prolonged abstinence syndrome compared to morphine.
LOE Approaching
Product approaching loss of exclusivity with limited commercial expansion opportunities; brand teams should focus on lifecycle management and competitive differentiation strategies.
Mechanism of Action
Mechanism of Action Methadone hydrochloride is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine, the most prominent of which involve the central nervous system and organs composed of smooth muscle. The principal therapeutic uses for…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on methadone offers limited growth trajectory given LOE-approaching status and minimal linked job postings (0 identified). Career value lies in lifecycle management expertise, managed care negotiation, and specialty pharmacy strategy rather than launch excitement or team expansion.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.