NDATOPICALOINTMENT
Approved
Jun 1960
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
MEDROL ACETATE (methylprednisolone acetate) by Pfizer is clinical pharmacology glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids. Approved for dermatomyositis, polymyositis, systemic lupus erythematosus and 4 more indications. First approved in 1960.
Drug data last refreshed 6d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MEDROL ACETATE (methylprednisolone acetate) is a topical glucocorticoid ointment approved in 1960 that treats inflammatory and autoimmune conditions including dermatomyositis, polymyositis, systemic lupus erythematosus, asthma, atopic dermatitis, ulcerative colitis, and rheumatoid arthritis. It works by modifying immune response and producing anti-inflammatory effects across multiple organ systems through glucocorticoid receptor activation.
LOE Approaching
Product approaching loss of exclusivity signals contraction; brand teams likely focused on lifecycle extension or transition planning with smaller support teams.
Mechanism of Action
CLINICAL PHARMACOLOGY Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt retaining properties, are used in replacement therapy in adrenocortical deficiency states. Their synthetic…
Indications (7)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.