MACRODANTIN

LOE Approaching

nitrofurantoin macrocrystals

NDAORALCAPSULE
Approved
Jun 1970
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

Mechanism of Action The mechanism of the antimicrobial action of nitrofurantoin is unusual among antibacterials. Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates which inactivate or alter bacterial ribosomal proteins and other acromolecules. As a result of such…

Pharmacologic Class:

Nitrofuran Antibacterial