LOREEV XR

Peak

lorazepam

NDAORALCAPSULE, EXTENDED RELEASE
Approved
Aug 2021
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
5

Mechanism of Action

gamma-aminobutyric acid-A (GABA A ) receptors in the brain and enhances GABA-mediated synaptic inhibition.

Pharmacologic Class:

Benzodiazepine

Clinical Trials (5)

NCT01994668Phase 1Completed

Phase 1 Study to Characterize the Safety and Pharmacokinetics of Single Intravenous Dose of Lorazepam in Healthy Japanese Adult Subjects

Started Jan 2014
8 enrolled
Healthy
NCT01275144Phase 1Completed

A Study of the Effect of LY2216684 on Lorazepam

Started Dec 2010
28 enrolled
Major Depressive Disorder
NCT00465244Phase 2/3Withdrawn

Seizure Therapy With Intravenous Levetiracetam and Lorazepam

Started Jan 2008
0
Seizures
NCT00546624Phase 2Completed

GEM 1.5 mg b.i.d. to 4.5 mg b.i.d. Versus Lorazepam in GAD (0777-026)

Started Nov 2002
38 enrolled
Anxiety Disorder
NCT00249171Phase 4Completed

A Study of Risperidone in Combination With Lorazepam Compared With Standard Therapy for Emergency Treatment of Schizophrenic Patients

Started Jun 2001
226 enrolled
SchizophreniaPsychotic DisordersEmergency Treatment

Loss of Exclusivity

LOE Date
Jan 8, 2034
95 months away
Patent Expiry
Jan 8, 2034

Patent Records (1)

Patent #ExpiryTypeUse Code
8999393
Jan 8, 2034
Product
U-3210