NDATOPICALCREAM
Approved
Sep 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
LOCOID LIPOCREAM (hydrocortisone butyrate) by Precision BioSciences is signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in atopic dermatitis is unknown. First approved in 1997.
Drug data last refreshed 19h ago · AI intelligence enriched 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LOCOID LIPOCREAM is a topical hydrocortisone butyrate cream approved in 1997 for inflammatory and pruritic dermatological conditions. It functions as a corticosteroid modulating immune signaling, inflammation, and protein regulation, though its precise mechanism in atopic dermatitis remains incompletely understood. This established dermatology product targets patients with eczema and other inflammatory skin disorders requiring topical steroid therapy.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100), suggesting brand defense and transition planning activities will dominate the commercial team's focus.
Mechanism of Action
signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in atopic dermatitis is unknown.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on LOCOID LIPOCREAM presents a defensive, mature-product career track focused on brand protection and market share retention rather than growth. This role suits professionals skilled in competitive analysis, pricing strategy, and portfolio management in a declining-franchise environment.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.