NDATOPICALCREAM
Approved
Sep 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
LOCOID LIPOCREAM (hydrocortisone butyrate) by Precision BioSciences is signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in atopic dermatitis is unknown. First approved in 1997.
Drug data last refreshed 26m ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LOCOID LIPOCREAM is a topical corticosteroid cream containing hydrocortisone butyrate, used to treat inflammatory skin conditions including atopic dermatitis. The drug works through immune signaling modulation and protein regulation, though its precise mechanism in atopic dermatitis remains incompletely understood. It is administered as a cream applied directly to affected skin areas.
LOE Approaching
Product is in late-stage lifecycle approaching loss of exclusivity, signaling a smaller, consolidating commercial team focused on defending market share against generics.
Mechanism of Action
signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in atopic dermatitis is unknown.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on LOCOID LIPOCREAM offers limited growth opportunities given the LOE-approaching lifecycle and zero linked job count, suggesting a small, consolidating team. Career value lies in gaining experience in generic defense, market maintenance, and cost optimization rather than launching or growing a product.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.