NDATOPICALCREAM
Approved
Sep 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
LOCOID LIPOCREAM (hydrocortisone butyrate) by Precision BioSciences is signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in atopic dermatitis is unknown. First approved in 1997.
Drug data last refreshed 14h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LOCOID LIPOCREAM is a topical corticosteroid cream containing hydrocortisone butyrate, a Class III potency steroid approved in 1997 for inflammatory skin conditions. The drug works by modulating immune signaling, inflammation, and protein regulation, though its precise mechanism in atopic dermatitis remains incompletely understood. It is administered as a topical cream for localized dermatological treatment.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30/100), signaling potential downsizing of brand support teams and transition to maintenance-mode operations.
Mechanism of Action
signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action in atopic dermatitis is unknown.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on LOCOID LIPOCREAM offers limited career growth given its approaching LOE and zero linked job openings; roles are primarily defensive commercial positions focused on managing decline rather than expansion. Career professionals should expect this assignment as a maintenance role with high risk of team restructuring.
Brand ManagerField Sales Representative
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.