NDAORALTABLETPriority Review
Approved
May 1983
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
Priority Review
LITHOSTAT (acetohydroxamic acid) by Mission Therapeutics is urease inhibitors [moa]. First approved in 1983.
Drug data last refreshed 16h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Lithostat (acetohydroxamic acid) is an oral urease inhibitor approved in 1983 for the prevention of struvite kidney stone formation. It works by inhibiting bacterial urease, an enzyme that promotes alkaline urine and stone precipitation in patients with recurrent urinary tract infections. This niche therapeutic is used in a small, stable patient population with specific metabolic or infectious stone disease.
$0.572MPart D
LOE ApproachingStable
Mature, niche product with minimal growth trajectory; small commercial team supporting a stable but declining patient base.
Mechanism of Action
Urease Inhibitors
Pharmacologic Class:
Urease Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Lithostat represents a mature, niche specialty product with minimal linked job openings, reflecting its small patient population and limited commercial expansion. Career opportunities on this product are constrained to lifecycle management and retention roles rather than growth-oriented positions.
Brand ManagerMedical Science Liaison
Worked on LITHOSTAT at Mission Therapeutics? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.