LEXAPRO

LOE Approaching

escitalopram

NDAORALTABLET
Approved
Aug 2002
Lifecycle
LOE Approaching
Competitive Pressure
35/100
Clinical Trials
20

Mechanism of Action

escitalopram, the S-enantiomer of racemic citalopram, is presumed to be linked to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).

Indications (1)

Clinical Trials (5)

NCT04388202Phase 4Withdrawn

Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram

Started Oct 2020
NCT03924323Phase 4Completed

A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder

Started May 2019
273 enrolled
Anxiety Disorders,Generalized Anxiety Disorder
NCT02191397Phase 3Completed

Study to Evaluate the Efficacy, Safety and Tolerability of Bupropion Hydrochloride Extended-release Tablet, and Escitalopram Oxalate Capsule in Subjects With Major Depressive Disorder

Started Feb 2015
534 enrolled
Depressive Disorder, Major
NCT01870843Phase 4Completed

A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom

Started Mar 2014
261 enrolled
Depressive Disorder, Major
NCT01418274Phase 1Completed

A Study to Evaluate the Effect of Danoprevir/Ritonavir on the Pharmacokinetics of Escitalopram and S-Demethylcitalopram in Healthy Volunteers

Started Aug 2011
20 enrolled
Healthy Volunteer

Loss of Exclusivity

LOE Date
May 12, 2026
2 months away
Exclusivity Expiry
May 12, 2026