ANDAORALTABLET, EXTENDED RELEASE
Approved
Apr 2000
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
3
Mechanism of Action
CLINICAL PHARMACOLOGY Mechanism of Action Isosorbide mononitrate extended-release tablet are an oral extended-release formulation of ISMN, the major active metabolite of isosorbide dinitrate; most of the clinical activity of the dinitrate is attributable to the mononitrate. The principal…
Pharmacologic Class:
Nitrate Vasodilator
Indications (1)
Clinical Trials (3)
Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial
Started Jan 2024
Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury
Started Sep 2019
9 enrolled
Kidney InjuryProteinuriaHypertension
Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)
Started Mar 2009
64 enrolled
Hypertension