NDAORALTABLET
Approved
Sep 2019
Lifecycle
Peak
Competitive Pressure
0/100
Mechanism of Action
sodium/hydrogen exchanger 3 (NHE3), an antiporter expressed on the apical surface of the small intestine and colon primarily responsible for the absorption of dietary sodium. In vitro and animal studies indicate its major metabolite, M1, is not active against NHE3. By inhibiting NHE3 on the apical…
Indications (1)
Loss of Exclusivity
LOE Date
Nov 26, 2042
203 months away
Patent Expiry
Nov 26, 2042
Company
Ardelyx
CA - Fremont