BLAINJECTIONINJECTABLE
Approved
Aug 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
GENOTROPIN (somatropin) by Pfizer is vitro, preclinical, and clinical tests have demonstrated that genotropin lyophilized powder is therapeutically equivalent to human growth hormone of pituitary origin and achieves similar pharmacokinetic profiles in normal adults. First approved in 1995.
Drug data last refreshed 11h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
GENOTROPIN (somatropin) is a recombinant human growth hormone (rHGH) therapeutic equivalent to pituitary-derived growth hormone used to treat growth hormone deficiency and related conditions in pediatric and adult populations. The drug works by stimulating linear growth, normalizing IGF-I concentrations, and inducing metabolic changes including reduced fat mass and improved lipid profiles. It is administered via subcutaneous injection and represents a foundational endocrinology therapy with nearly 30 years of clinical use.
$27MPart D
LOE ApproachingAs LOE approaches, GENOTROPIN brand teams are transitioning from growth-focused strategies to market defense and lifecycle extension initiatives; team size likely consolidating.
Mechanism of Action
vitro, preclinical, and clinical tests have demonstrated that GENOTROPIN lyophilized powder is therapeutically equivalent to human growth hormone of pituitary origin and achieves similar pharmacokinetic profiles in normal adults. In pediatric patients who have growth hormone deficiency (GHD), have…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
The Efficacy and Safety of Inpegsomatropin Injection in Children With Turner Syndrome (TS) and Short Stature
Started Jul 2026
84 enrolled
Turner Syndrome
Safety, Pharmacokinetic (PK) Profile and Efficacy of Inpegsomatropin Injection in Adults With Growth Hormone Deficiency
Started Jun 2026
36 enrolled
Adult Growth Hormone Deficiency
A Study to Learn How Different Injector Pens Affect the Study Medicine Called Genotropin (Somatropin) Delivery and Taken up Into the Blood in Healthy Adults
Started Apr 2026
26 enrolled
Healthy
Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.
Started Feb 2026
254 enrolled
ISSSGA
The Efficacy and Safety of Inpegsomatropin Injection in Children With Short Stature Born Small for Gestational Age
Started Jan 2026
141 enrolled
Small for Gestational Age
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.