BLAINJECTIONINJECTABLE
Approved
Aug 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
6/8 — Strong
GENOTROPIN (somatropin) by Pfizer is vitro, preclinical, and clinical tests have demonstrated that genotropin lyophilized powder is therapeutically equivalent to human growth hormone of pituitary origin and achieves similar pharmacokinetic profiles in normal adults. First approved in 1995.
Drug data last refreshed 26m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
GENOTROPIN (somatropin) is a recombinant human growth hormone approved in 1995 for treating growth hormone deficiency and multiple pediatric conditions including Prader-Willi syndrome, Turner syndrome, and idiopathic short stature. It works by stimulating linear growth and normalizing IGF-I concentrations, increasing lean body mass and reducing fat mass in both pediatric and adult patients. The product is administered via subcutaneous injection.
$0.027BPart D
LOE ApproachingProduct approaching loss of exclusivity with moderate Part D utilization; brand team likely focused on lifecycle extension and managed care retention strategies.
Mechanism of Action
vitro, preclinical, and clinical tests have demonstrated that GENOTROPIN lyophilized powder is therapeutically equivalent to human growth hormone of pituitary origin and achieves similar pharmacokinetic profiles in normal adults. In pediatric patients who have growth hormone deficiency (GHD), have…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
A Clinical Study of Long-Term Administration of Inpegsomatropin Injection in Participants With Idiopathic Short Stature Who Have Completed Phase Ⅲ Clinical Trials
Started Sep 2026
300 enrolled
Idiopathic Short Stature
The Efficacy and Safety of Inpegsomatropin Injection in Children With Turner Syndrome (TS) and Short Stature
Started Jul 2026
84 enrolled
Turner Syndrome
Safety, Pharmacokinetic (PK) Profile and Efficacy of Inpegsomatropin Injection in Adults With Growth Hormone Deficiency
Started Jun 2026
36 enrolled
Adult Growth Hormone Deficiency
A Study to Learn How Different Injector Pens Affect the Study Medicine Called Genotropin (Somatropin) Delivery and Taken up Into the Blood in Healthy Adults
Started Apr 2026
27 enrolled
Healthy
Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.
Started Feb 2026
254 enrolled
ISSSGA
Worked on GENOTROPIN at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.