NDAORALTABLET
Approved
Nov 2001
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
FROVA (frovatriptan succinate) by Leadingtac Pharmaceutical is 5-ht 1b/1d receptors. Approved for migraine attacks, cluster headache, migraine. First approved in 2001.
Drug data last refreshed 2d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
FROVA (frovatriptan succinate) is an oral triptan approved in 2001 for acute migraine and cluster headache treatment. It works by agonizing 5-HT 1B/1D receptors on intracranial blood vessels and trigeminal sensory nerves, causing cranial vasoconstriction and inhibiting pro-inflammatory neuropeptide release.
$0.357MPart D
LOE ApproachingDeclining
As LOE approaches with minimal Part D spending ($357K in 2023), the brand team is likely contracting; career focus shifts to generic partnerships or portfolio optimization roles.
Mechanism of Action
5-HT 1B/1D receptors. The therapeutic activity of frovatriptan succinate is thought to be due to the agonist effects at the 5-HT 1B/1D receptors on intracranial blood vessels (including the arterio-venous anastomoses) and sensory nerves of the trigeminal system which result in cranial vessel…
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.