NDAORALTABLET
Approved
Jan 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
EXCEDRIN (MIGRAINE RELIEF) (acetaminophen, asprin, caffeine) by GSK is cyclooxygenase inhibitors [moa]. Approved for migraine. First approved in 1998.
Drug data last refreshed 1w ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Excedrin Migraine is a fixed-dose oral tablet combining acetaminophen, aspirin, and caffeine, indicated for acute migraine relief. It works via cyclooxygenase inhibition (NSAID mechanism) combined with caffeine's cranial vasoconstrictive properties to reduce migraine pain and associated symptoms. This over-the-counter combination targets patients seeking rapid, accessible relief without prescription barriers.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100); small team size typical of mature OTC brands focused on brand defense and generic transition planning.
Mechanism of Action
Cyclooxygenase Inhibitors
Pharmacologic Class:
Nonsteroidal Anti-inflammatory Drug
Indications (1)
Career Relevance
Excedrin careers focus on defending market share in an OTC channel against generic competitors and prescription alternatives, offering solid commercial execution experience but limited innovation exposure. Roles emphasize retail partnerships, consumer marketing, and lifecycle management skills relevant to mature brand portfolios.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.