NDAORALTABLET
Approved
Jan 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
EXCEDRIN (MIGRAINE RELIEF) (acetaminophen, asprin, caffeine) by GSK is cyclooxygenase inhibitors [moa]. Approved for migraine. First approved in 1998.
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Excedrin Migraine Relief is an over-the-counter combination tablet containing acetaminophen, aspirin, and caffeine used to treat migraine headaches. It works as a cyclooxygenase inhibitor with anti-inflammatory properties, leveraging caffeine as an adjunctive agent to enhance efficacy. The triple-component formulation addresses pain relief while the stimulant component aids absorption and blood vessel constriction.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100) indicates brand team focus shifting toward retention and line extension rather than growth.
Mechanism of Action
Cyclooxygenase Inhibitors
Pharmacologic Class:
Nonsteroidal Anti-inflammatory Drug
Indications (1)
Career Relevance
Excedrin roles focus on defending market share in an increasingly competitive OTC migraine category against prescription triptans and emerging biologics. Career growth requires expertise in consumer marketing, OTC regulatory strategy, and competitive repositioning rather than clinical development or innovative therapy expansion.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.