NDATOPICALCREAM
Approved
Dec 2003
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
ERTACZO (sertaconazole nitrate) by Lacer is 12. First approved in 2003.
Drug data last refreshed 7h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ERTACZO (sertaconazole nitrate) is a topical azole antifungal cream approved in 2003 for treating fungal skin infections, including interdigital tinea pedis caused by Trichophyton rubrum, T. mentagrophytes, and Epidermophyton floccosum. The drug works by inhibiting fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylase, disrupting ergosterol synthesis and compromising fungal cell membrane integrity. Minimal systemic absorption occurs with topical application.
$0.942MPart D
LOE ApproachingProduct is in late-stage lifecycle with minimal claims volume, indicating a small commercial footprint and likely streamlined support team focused on maintenance rather than growth.
Mechanism of Action
12.1 Mechanism of Action Sertaconazole nitrate is an azole antifungal [see ] . 12.2 Pharmacokinetics In a multiple-dose pharmacokinetic trial that included 5 male subjects with interdigital tinea pedis (range of diseased area, 42 - 140 cm ; mean, 93 cm ), ERTACZO cream, 2%, was topically applied…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Arasertaconazole Nitrate Pessaries - Dose Finding Study for the Vulvovaginal Candidiasis (VVC) Treatment
Started Jun 2010
229 enrolled
Vulvovaginal Candidiasis
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.