NDAORALTABLET
Approved
Aug 2004
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
5
Mechanism of Action
Mechanism of Action: Abacavir is a carbocyclic synthetic nucleoside analogue. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP), an analogue of deoxyguanosine-5′-triphosphate (dGTP). CBV-TP inhibits the activity of HIV-1 reverse transcriptase (RT)…
Indications (1)
Clinical Trials (5)
Study of Maraviroc (MVC) and Epzicom (ABC/3TC) Once-Daily in ART-Naive & First Switch Patients
Started Jul 2012
51 enrolled
Drug-induced Hypotension
A Simplification Study of Unboosted Reyataz With Epzicom (ASSURE)
Started Apr 2010
297 enrolled
Infection, Human Immunodeficiency Virus
Safety and Efficacy Study of Switching From Epzicom to Truvada
Started Jul 2008
312 enrolled
HIV Infection
Pilot Study With Isentress (Raltegravir) and Epzicom (Abacavir/Lamivudine) in Treatment Naive HIV-Infected Subjects
Started May 2008
30 enrolled
HIV Infections
Pharmacokinetic Study Of EPZICOM Tablet
Started Jul 2006
8 enrolled
HIV Infection