EPCLUSA

Peak

velpatasvir and sofosbuvir

NDAORALPELLETSPriority Review
Approved
Jun 2021
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
2

Mechanism of Action

Breast Cancer Resistance Protein Inhibitors

Pharmacologic Class:

Hepatitis C Virus NS5A Inhibitor

Clinical Trials (2)

NCT03549312Phase 4Unknown

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Started Feb 2018
25 enrolled
HIV-1-infectionHepatitis C, ChronicMethadone Dependence+6 more
NCT01260350Phase 2Completed

Open-Labeled Study of PSI-7977 and RBV With and Without PEG-IFN in Treatment-Naïve Patients With HCV GT2 or GT3

Started Dec 2010
292 enrolled
Chronic Hepatitis C Infection

Loss of Exclusivity

LOE Date
Jul 30, 2034
102 months away
Patent Expiry
Jul 30, 2034
Exclusivity Expiry
Dec 10, 2028

Patent Records (5)

Patent #ExpiryTypeUse Code
8580765
Mar 21, 2028
SubstanceProduct
U-1470
9085573
Mar 21, 2028
SubstanceProduct
U-1470
8735372
Mar 21, 2028
U-1470
8334270
Mar 21, 2028
SubstanceProduct
U-1470
8334270*PED
Sep 21, 2028