ELZONRIS

Peak

tagraxofusp

BLAINJECTIONSOLUTIONPriority Review
Approved
Dec 2018
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
9

Mechanism of Action

CD123 Interactions

Pharmacologic Class:

CD123 Interaction

Clinical Trials (5)

NCT07148180Phase 1/2Recruiting

A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax

Started Feb 2026
31 enrolled
Acute Myeloid Leukaemia (AML)LeukemiaBlood Cancer+1 more
NCT07007052Phase 2Not Yet Recruiting

Phase II Study Evaluating the Efficacy and Safety of the Combination of Tagraxofusp and Venetoclax in Treatment-naive Blastic Plasmacytoid Dendritic Cell Neoplasm Patients

Started Dec 2025
33 enrolled
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
NCT06561152Phase 1/2Recruiting

Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML

Started Feb 2025
20 enrolled
Refractory Acute Myeloid LeukemiaRelapsed Acute Myeloid Leukemia
NCT06498973Phase 1Recruiting

Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant

Started Jan 2025
NCT06456463Phase 2Recruiting

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Started Jan 2025
83 enrolled
Acute Myeloid Leukemia