BLAINTRAVENOUSVIAL
Approved
Jul 2002
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
15
Data completeness
6/8 — Strong
ELITEK (rasburicase) by Sanofi is humans, uric acid is the final step in the catabolic pathway of purines. Approved for hyperuricemia, tumor lysis syndrome. First approved in 2002.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ELITEK (rasburicase) is a recombinant urate oxidase administered intravenously that catalyzes enzymatic oxidation of uric acid into the inactive, soluble metabolite allantoin. It is indicated for hyperuricemia in patients with hematologic malignancies (lymphoma, leukemia) at risk of tumor lysis syndrome.
$571KPart D
LOE ApproachingNiche IV biologic with minimal Medicare Part D footprint approaching loss of exclusivity, indicating small brand team and stable but limited commercial opportunity.
Mechanism of Action
humans, uric acid is the final step in the catabolic pathway of purines. Rasburicase catalyzes enzymatic oxidation of poorly soluble uric acid into an inactive and more soluble metabolite (allantoin).
Indications (2)
Clinical Trials (15)
MIELITEKO Lifestyle Intervention Study
Started Aug 2022
Evaluate the Efficacy and Safety of Rasburicase (Fasturtec®) in the Prevention and Treatment of Hyperuricemia in Pediatric Patients With Non-Hodgkin's Lymphoma and Acute Leukemia
Started May 2020
50 enrolled
Lymphoma
Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2
Started Apr 2011
55 enrolled
LeukemiaLymphoma
Elitek (Rasburicase) Immuno-Monitoring Study
Started Feb 2010
1 enrolled
Tumor Lysis Syndrome
Rasburicase in Patients at Risk for Tumor Lysis Syndrome
Started Jan 2008
82 enrolled
Tumor Lysis Syndrome
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.