NDAINJECTIONINJECTABLE
Approved
Oct 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
Mechanism of Action Epidurally administered clonidine produces dose-dependent analgesia not antagonized by opiate antagonists. The analgesia is limited to the body regions innervated by the spinal segments where analgesic concentrations of clonidine are present. Clonidine is thought to produce…