NDAINJECTIONINJECTABLE
Approved
Oct 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
DURACLON (clonidine hydrochloride) by Viatris is mechanism of action epidurally administered clonidine produces dose-dependent analgesia not antagonized by opiate antagonists. First approved in 1996.
Drug data last refreshed 13h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DURACLON (clonidine hydrochloride) is an epidural injectable alpha-2 adrenergic agonist approved in 1996 for spinal analgesia. It works by blocking pain signal transmission at presynaptic and postjunctional alpha-2 adrenoceptors in the spinal cord, producing analgesia limited to innervated spinal segments. The drug is indicated for severe cancer pain in patients tolerant to opioids.
LOE Approaching
With LOE approaching and minimal current linked roles, this product represents a niche, mature specialty franchise with limited growth opportunity and a small, specialized team.
Mechanism of Action
Mechanism of Action Epidurally administered clonidine produces dose-dependent analgesia not antagonized by opiate antagonists. The analgesia is limited to the body regions innervated by the spinal segments where analgesic concentrations of clonidine are present. Clonidine is thought to produce…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on DURACLON offers limited career expansion given the product's niche indication, approaching LOE, and minimal open roles. This role is best suited for specialists seeking deep expertise in oncology pain management or transition into legacy product management.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.