DUONEB

LOE Approaching

albuterol sulfate; ipratropium bromide

NDAINHALATIONSOLUTION

Approved

Mar 2001

Lifecycle

LOE Approaching

Competitive Pressure

30/100

Mechanism of Action

CLINICAL PHARMACOLOGY The prime action of beta-adrenergic drugs is to stimulate adenyl cyclase, the enzyme which catalyzes the formation of cyclic-3',5'-adenosine monophosphate (cyclic AMP) from adenosine triphosphate (ATP). The cyclic AMP thus formed mediates the cellular responses. In vitro…

External Resources

DailyMed

Full prescribing information

FDA Drugs@FDA

FDA approval history

RxNorm

Drug nomenclature & identifiers