DOXORUBICIN HYDROCHLORIDE (doxorubicin hydrochloride) by Fresenius Kabi is clinical pharmacology: the cytotoxic effect of doxorubicin on malignant cells and its toxic effects on various organs are thought to be related to nucleotide base intercalation and cell membrane lipid binding activities of doxorubicin. Approved for breast cancer, leukemia, lymphoma. First approved in 1995.
Drug data last refreshed 19h ago
CLINICAL PHARMACOLOGY: The cytotoxic effect of doxorubicin on malignant cells and its toxic effects on various organs are thought to be related to nucleotide base intercalation and cell membrane lipid binding activities of doxorubicin. Intercalation inhibits nucleotide replication and action of DNA…
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