DOFETILDE (dofetilide) by Aurobindo Pharma is clinical pharmacology mechanism of action dofetilide shows vaughan williams class iii antiarrhythmic activity. Approved for atrial fibrillation, atrial fibrillation. First approved in 2019.
Drug data last refreshed 18h ago
CLINICAL PHARMACOLOGY Mechanism of Action Dofetilide shows Vaughan Williams Class III antiarrhythmic activity. The mechanism of action is blockade of the cardiac ion channel carrying the rapid component of the delayed rectifier potassium current, I Kr . At concentrations covering several orders of…
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Antiarrhythmic
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Effect of Oral GS-6615 on Dofetilide-Induced QT Prolongation, Safety, and Tolerability in Healthy Adults