DESLORATADINE

Post-LOE

desloratadine

Design Pharmaceuticals

ANDAORALSOLUTION

Approved

Jun 2015

Lifecycle

Post-LOE

Competitive Pressure

30/100

Clinical Trials

Data completeness

4/8 — Partial

DESLORATADINE (desloratadine) by Design Pharmaceuticals is long-acting tricyclic histamine antagonist with selective h 1 -receptor histamine antagonist activity. First approved in 2015.

Drug data last refreshed 19h ago

$0.0BPart D

Mechanism of Action

long-acting tricyclic histamine antagonist with selective H 1 -receptor histamine antagonist activity. Receptor binding data indicates that at a concentration of 2 to 3 ng/mL (7 nanomolar), desloratadine shows significant interaction with the human histamine H 1 -receptor. Desloratadine inhibited…

Indications

Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.

Clinical Trials (14)

NCT02904304Phase 3Suspended

Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu

Started Dec 2020

150 enrolled

Cold

NCT01529242Phase 3Terminated

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment

Started Feb 2014

17 enrolled

Cutaneous Hypersensitivity

NCT01529229Phase 3Completed

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment

Started Nov 2013

210 enrolled

Allergic Rhinitis

NCT01720485Phase 3Unknown

Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment

Started Oct 2013

234 enrolled

Allergic Rhinitis

NCT01506791Phase 1Completed

Bioequivalence Study of Desloratadine and Pseudoephedrine Extended-release Tablets Under Fed Conditions

Started Apr 2006

44 enrolled

Healthy

Worked on DESLORATADINE at Design Pharmaceuticals? Share your interview experience or compensation data (+7 days Pro)

Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.