NDAORALELIXIR
Approved
Jul 1960
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
DECADRON (dexamethasone) by Merck & Co. is clinical pharmacology naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Approved for multiple myeloma, postoperative nausea and vomiting. First approved in 1960.
Drug data last refreshed 20h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DECADRON (dexamethasone) is a synthetic glucocorticoid approved in 1960 that works through potent anti-inflammatory mechanisms by modifying immune responses and metabolic effects. It is indicated for multiple myeloma and postoperative nausea and vomiting as an oral elixir formulation. Unlike hydrocortisone, dexamethasone lacks sodium-retaining properties at equipotent anti-inflammatory doses.
LOE Approaching
As a near-LOE product with minimal linked job activity, this represents a mature, stable portfolio asset with limited commercial expansion opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY Naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, including dexamethasone, are primarily used for their potent…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.