DAUNORUBICIN HYDROCHLORIDE (daunorubicin hydrochloride) by Thayer Medical is mechanism of action daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action. Approved for leukemia. First approved in 2000.
Drug data last refreshed 19h ago
Mechanism of Action Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action. Daunorubicin forms complexes with DNA by intercalation between base pairs. It inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the…
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