DAPAGLIFLOZIN;METFORMIN HYDROCHLORIDE (dapagliflozin; metformin hydrochloride) by Teva is sodium-glucose cotransporter 2 (sglt2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Approved for end stage kidney disease, cardiovascular death, hospitalization for heart failure in patients with chronic kidney disease at risk of progression and 7 more indications.
Drug data last refreshed 1mo ago
Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose, and…
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