Mechanism of Action
β-adrenoreceptor blocking activity is present in the S(-) enantiomer and α 1 -adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilol has no intrinsic sympathomimetic activity.
Indications (12)
Clinical Trials (5)
Efficacy of Coreg CR and Lisinopril on Markers for Cardiovascular Functional and Structural Disease
Study to Examine the Effect of Food on the Pharmacokinetics of the Fixed Dose Combination of COREG CR and Lisinopril.
A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure
Study to Demonstrate the Bioequivalence of the Fixed Dose Combination of COREG CR™ and Lisinopril to Its Components
Study to Investigate Dose Proportionality of the Fixed Dose Combination of COREG CR and Lisinopril.
Loss of Exclusivity
Patent Records (2)
| Patent # | Expiry | Type | Use Code |
|---|---|---|---|
| 8101209 | Sep 11, 2025Expired | Product | — |
| 8101209*PED | Mar 11, 2026 | — |