CONJUGATED ESTROGENS

Post-LOE

estrogens, conjugated

Pfizer

ANDAORALTABLET

Approved

Oct 2025

Lifecycle

Post-LOE

Competitive Pressure

30/100

Clinical Trials

Data completeness

4/8 — Partial

CONJUGATED ESTROGENS (estrogens, conjugated) by Pfizer is estrogen receptor agonists [moa]. Approved for moderate to severe vasomotor symptoms due to menopause, moderate to severe vulvar, vaginal atrophy due to menopause () and 10 more indications. First approved in 2025.

Drug data last refreshed 19h ago

Mechanism of Action

Estrogen Receptor Agonists

Pharmacologic Class:

Estrogen

Indications (12)

Moderate to Severe Vasomotor Symptoms due to Menopause Moderate to Severe Vulvar

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Clinical Trials (12)

NCT02100553Phase 1Completed

Study Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal Women

Started Apr 2014

24 enrolled

Healthy

NCT01634789Phase 1Terminated

A Pilot Bioavailability Study of 3 Test Tablet Formulations of Bazedoxifene Compared With A Reference Tablet Formulation of Bazedoxifene/Conjugated Estrogens in Healthy Postmenopausal Women

Started Aug 2012

2 enrolled

Healthy

NCT00847821N/ATerminated

Observational Study Analyzing RNA Expression Of Endometrial Biopsy Samples From Placebo, Bazedoxifene/Conjugated Estrogens And Raloxifene

Started May 2009

185 enrolled

Postmenopause

NCT00808132Phase 3Completed

Study Evaluating The Effects Of Bazedoxifene/Conjugated Estrogens On Endometrial Safety And Postmenopausal Osteoporosis

Started Jan 2009

1,886 enrolled

MenopauseOsteoporosis

NCT00592839Phase 4Completed

Study to Evaluate the Effects of Synthetic Conjugated Estrogens, B (SCE-B) on Nocturnal Vasomotor Symptoms in Postmenopausal Women

Started Dec 2007

157 enrolled

Nocturnal Vasomotor Symptoms