NDAVAGINALCREAM
Approved
Aug 1992
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
5/8 — Partial
CLEOCIN (clindamycin phosphate) by Pfizer is mechanism of action clindamycin is an antibacterial drug (see ) . Approved for acne vulgaris, bacterial vaginosis. First approved in 1992.
Drug data last refreshed 20h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CLEOCIN (clindamycin phosphate) is a small-molecule antibacterial antibiotic available as a vaginal cream for treating acne vulgaris and bacterial vaginosis. It works by inhibiting bacterial protein synthesis, making it effective against a broad spectrum of gram-positive and anaerobic organisms.
LOE Approaching
As LOE approaches, the CLEOCIN franchise faces declining revenue pressure and likely reduced headcount in brand management and field sales roles.
Mechanism of Action
Mechanism of Action Clindamycin is an antibacterial drug (see ) .
Indications (2)
Clinical Trials (4)
Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris
Started Oct 2025
200 enrolled
Acne Vulgaris
Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide
Started Jan 2017
22 enrolled
Actinic Keratosis
A Efficacy and Safety of Duac™Compared With Clindamycin Phosphate Gel in the Treatment of Mild to Moderate Acne Vulgaris
Started Apr 2013
1,018 enrolled
Acne Vulgaris
W0265-104: A Single-Center, Evaluator-Blinded, Randomized, Placebo-Controlled, Phase 1 Clinical Trial Evaluating the Photoallergic Potential of Topically Applied Clindamycin Phosphate 1.0% and Tretinoin 0.025% (CT Gel) in Healthy Volunteers
Started Nov 2008
64 enrolled
Acne Vulgaris
Worked on CLEOCIN at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.